Cardiac Complications in Juvenile Hyperthyroidism

Dilated cardiomyopathy with Graves disease in a young child

“…However, some patients with cardiomyopathy due to hyperthyroidism have died in spite of medical treatment 9 10) . Childhood GD is not as common as the adult form and, moreover, the incidence of severe cardiac complications is also lower, being seen in only 1% of these patients 7) . Cavallo et al 7) reported that 2 of 21 children with hyperthyroidism had congestive heart failure.…”

“…Childhood GD is not as common as the adult form and, moreover, the incidence of severe cardiac complications is also lower, being seen in only 1% of these patients 7) . Cavallo et al 7) reported that 2 of 21 children with hyperthyroidism had congestive heart failure. One of the 2 patients, who was diagnosed with hyperthyroidism at 12 years of age, underwent subtotal thyroidectomy but deteriorated because of cardiac complications and died of possible cerebral embolism.…”

Graves’ Thyrotoxicosis-Induced Reversible Cardiomyopathy: A Case Report

“…In hyperthyroidism, heart failure may occur in the absence of underlying heart disease as reported in children by Cavallo et al 4 Reduced left ventricular contractile reserve may impair the ability to raise cardiac output to match the increase of peripheral metabolic demand. Left ventricular hypertrophy may result in impaired left ventricular filling, in particular when associated with accelerated heart rate.…”

Paradoxical euthyroid hormone profile in a case of Graves' disease with cardiac failure

“…There are very few reports of cardiac failure in juvenile hyperthyroidism. In a retrospective analysis of 21 children with hyperthyroidism, cardiac failure was observed in 2 patients [3]. There is some evidence of presence of thyrotoxic cardiomyopathy in children [8].…”