Carcinoma of the Larynx in a Girl Aged 15

Abstract

A review of the literature on juvenile cancer reveals conflicting views regarding the incidence, course, and general significance of this group of diseases, and these conflicts are clearly referable to the difference in the age periods included in the material considered by the authors. The writers who included under juvenile cancer all cases occurring in the first three decades failed to be impressed by any special characters of cancer in these periods and were inclined to dismiss the subject as of no special interest. On the other hand, the authors who considered especially the tumors occurring in the earlier age periods and particularly those occurring in infancy and the first decade were uniformly impressed with many peculiarities of cancer in childhood. There is a marked increase in the incidence of cancer in the third decade, and, when all these cases are included, the facts of interest regarding cancer in infancy and childhood are submerged and overlooked.It is now very well known that in the third decade cancer occurs rather fre¬ quently and does not differ materially from similar diseases in adult life. Real interest, however, attaches to the malignant neoplasms which occur in infancy and childhood up to 10 or 15 years, when special factors of heredity, nutrition, and growth may be expected to express themselves.Quoting again, this time from Hayes E. Martin 2 :This relative infrequency of cancer in children is not a true index of its sig¬ nificance, however, for, while most childhood diseases have a low mortality rate, cancer in the young is a highly malignant and fatal disease, as is proved by the mortality statistics already cited by Dr. Dargeon.3 Cancer of the head and neck is less than }ioo times as frequent in children as in adults.

Carcinoma of the larynx in childhood

“…In I of these cases, the patient died of radiation myelitis, even though the tumor had been eradicated. 22 Six of the deaths due to tumor occurred within one year. Since all but 3 patients received radiation therapy and all but 5, partial or total laryngectomy, the relative merits of radiotherapy and surgery cannot be assessed.…”

Carcinoma larynx in a 10-year-old girl: a rare clinical entity

“…Nevertheless, physicians must be aware that a small percentage of cases do occur in the pediatric age group since case reports in patients less than 15 years of age, laryngeal cancers accounts for less than 0.1% of all head and neck malignancies 13,14,15 . In a survey of 98 cases of carcinoma of the larynx in patients less than 20 years of age, have about 20 cases in the 12 and under age group 3 .…”

Pediatric Laryngeal Malignancies: Current Management Protocols and Review of Literature

“…2 So a remote differential diagnosis should be in mind as laryngeal cancers in pediatric population accounts for less than 0.1% of all head and neck malignancies. [6][7][8] Incidence in female are nearly equal to male in pediatric laryngeal cancer (female 40% in pediatric, 10% in adult cancer). 3 Risk factor include previous irradiation of papilloma, papillomatosis, malnutrition and human papilloma virus (HPV) infection.…”