Carcinogenic potential, levels and sources of polycyclic aromatic hydrocarbon mixtures in indoor and outdoor environments and their implications for air quality standards

Delgado-Saborit, Juana María; Stark, Christopher; Harrison, Roy M.

doi:10.1016/j.envint.2010.10.011

Cited by 186 publications

(166 citation statements)

References 57 publications

Supporting

Mentioning

140

Contrasting

Unclassified

Order By: Relevance

“…Among the many PAHs, benzo(a)pyrene (BaP) is one of the most highly carcinogenic agents. BaP is used as an indicator of cancer risk from exposure to PAH mixtures (4,5), and is also a criteria pollutant in many countries.…”

mentioning

confidence: 99%

Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol

Shrivastava

Lou

Zelenyuk

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

215

228

View full text Add to dashboard Cite

Polycyclic aromatic hydrocarbons (PAHs) have toxic impacts on humans and ecosystems. One of the most carcinogenic PAHs, benzo(a)pyrene (BaP), is efficiently bound to and transported with atmospheric particles. Laboratory measurements show that particle-bound BaP degrades in a few hours by heterogeneous reaction with ozone, yet field observations indicate BaP persists much longer in the atmosphere, and some previous chemical transport modeling studies have ignored heterogeneous oxidation of BaP to bring model predictions into better agreement with field observations. We attribute this unexplained discrepancy to the shielding of BaP from oxidation by coatings of viscous organic aerosol (OA). Accounting for this OA viscosity-dependent shielding, which varies with temperature and humidity, in a global climate/chemistry model brings model predictions into much better agreement with BaP measurements, and demonstrates stronger long-range transport, greater deposition fluxes, and substantially elevated lung cancer risk from PAHs. Model results indicate that the OA coating is more effective in shielding BaP in the middle/high latitudes compared with the tropics because of differences in OA properties (semisolid when cool/dry vs. liquid-like when warm/humid). Faster chemical degradation of BaP in the tropics leads to higher concentrations of BaP oxidation products over the tropics compared with higher latitudes. This study has profound implications demonstrating that OA strongly modulates the atmospheric persistence of PAHs and their cancer risks.

show abstract

mentioning

confidence: 99%

Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol

Shrivastava

Lou

Zelenyuk

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

215

228

View full text Add to dashboard Cite

show abstract

“…TEFs from Nisbet and LaGoy (1992) were used as the most reliable indexes for studies on the toxicity of PAHs in atmospheric particulate matter and to be consistent with similar recent studies (e.g., Silva et al, 2010;Han et al, 2011;Delgado-Saborit et al, 2011;Masiol et al, 2012a;Cristale et al, 2012;Zhou and Zhao, 2012). Similarly, just with the replacement of TEF with MEF (Mutagenic Equivalency Factors) proposed by Durant et al (1996), the mutagenicity related to BaP (BaP MEQ ) was also calculated.…”

Section: Toxic and Mutagenic Equivalency Factorsmentioning

confidence: 89%

Seasonal trends and spatial variations of PM10-bounded polycyclic aromatic hydrocarbons in Veneto Region, Northeast Italy

Masiol

Formenton

Pasqualetto

et al. 2013

Atmospheric Environment

View full text Add to dashboard Cite

“…Traffic areas, e.g. highway tunnel [9], road intersection [14], traffic roadside [15], distribution center and bus terminal [16], etc., all showed significantly higher airborne PAH levels than common urban areas. Data also indicate that traffic-related workers, e.g.…”

Section: Introductionmentioning

confidence: 99%

Occurrence and carcinogenic potential of airborne polycyclic aromatic hydrocarbons in some large-scale enclosed/semi-enclosed vehicle parking areas

Zeng

Zhang

et al. 2014

Journal of Hazardous Materials

View full text Add to dashboard Cite

Carcinogenic potential, levels and sources of polycyclic aromatic hydrocarbon mixtures in indoor and outdoor environments and their implications for air quality standards

Cited by 186 publications

References 57 publications

Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol

Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol

Seasonal trends and spatial variations of PM10-bounded polycyclic aromatic hydrocarbons in Veneto Region, Northeast Italy

Occurrence and carcinogenic potential of airborne polycyclic aromatic hydrocarbons in some large-scale enclosed/semi-enclosed vehicle parking areas

Contact Info

Product

Resources

About