Carbohydrate‐rich snacks influence plasma glucose, insulin and ghrelin responses in overweight adults (1039.5)

Abstract

The effects of a whole food (dried plums; DP) or refined (low‐fat muffins; LFM) snack on satiety and insulin responses following consumption were assessed before and after a snack intervention trial. Forty overweight men and women (age: 36.5 + 11.4, BMI: 32.8 + 7.1 kg/m2) were randomly assigned to consume isocaloric, macronutrient‐matched 100 kcal snacks twice per day of DP or LFM for 8‐weeks. At baseline and 8 weeks, fasted subjects consumed 238 kcal of their randomly assigned food, and blood samples were collected at baseline, 15, 30, 45, 60, 90, and 120 min following intake. Insulin was lower (p蠄0.05) and an earlier peak was observed in DP versus LFM at baseline and 8 weeks. Both groups exhibited lower plasma glucose during the acute response testing after 8 weeks, but glucose peaked earlier in DP than LFM. There were no significant differences in ghrelin concentration over time in either group. These results support the concept that consuming a whole food snack such as dried plums enhances insulin sensitivity as compared to an isocaloric refined snack food, as evidenced by lower insulin concentrations and an earlier peak in insulin and glucose in DP compared to LFM. Grant Funding Source: Supported by the California Dried Plum Board