We propose a mathematical model for cholera with treatment through
quarantine. The model is shown to be both epidemiologically and mathematically
well posed. In particular, we prove that all solutions of the model are
positive and bounded; and that every solution with initial conditions in a
certain meaningful set remains in that set for all time. The existence of
unique disease-free and endemic equilibrium points is proved and the basic
reproduction number is computed. Then, we study the local asymptotic stability
of these equilibrium points. An optimal control problem is proposed and
analyzed, whose goal is to obtain a successful treatment through quarantine. We
provide the optimal quarantine strategy for the minimization of the number of
infectious individuals and bacteria concentration, as well as the costs
associated with the quarantine. Finally, a numerical simulation of the cholera
outbreak in the Department of Artibonite (Haiti), in 2010, is carried out,
illustrating the usefulness of the model and its analysis.Comment: This is a preprint of a paper whose final and definite form is with
'Journal of Computational and Applied Mathematics', ISSN 0377-0427, available
at [http://dx.doi.org/10.1016/j.cam.2016.11.002]. Submitted 19-June-2016;
Revised 14-Sept-2016; Accepted 04-Nov-2016. This version: some typos detected
while reading the proofs were correcte