Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.01.067 View full text
Laszlo Prokai, Szabolcs Szarka, Xiaoli Wang, Katalin Prokai-Tatrai

Abstract: Carbonyl compounds are common byproducts of many metabolic processes. These volatile chemical entities are usually derivatized before mass spectrometric analysis to enhance the sensitivity of their detections. The classically used reagent for this purpose is 2,4-dinitrophenylhydrazine (DNPH) that forms the corresponding hydrazones. When DNPH is immobilized on specific cartridges it permits solvent-free collection and simultaneous derivatization of aldehydes and ketones from gaseous samples. The utility of thi…

expand abstract