“…C. albicans is the species implicated in most CNS infections, but other species such as Candida tropicalis, Candida lusitaniae, and Candida parapsilosis occasionally produce CNS disease. [71][72][73][74][75] In the normal host, Candida rarely causes deepseated infections. Factors that can encourage spread of Candida from mucosal surfaces to deeper tissues, such as the subarachnoid space, include prematurity, broad-spectrum antibacterial therapy, hyperalimentation, malignancy, indwelling catheters, treatment with corticosteroids, neutropenia, abdominal surgery, diabetes mellitus, burns, and intravenous drug use.…”