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Cited by 178 publications
(121 citation statements)
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“…Indeed, in our study C. parapsilosis complex was the species most frequently isolated in IVD-related candidaemia, both in the ICU and in the surgical wards, and the relationship with the biofilm production of these strains was investigated very recently [28]. Therefore, despite the fact that C. parapsilosis complex has long been considered to be a low-virulence species [29], our observation that C. parapsilosis complex was the main species involved in IVD-related candidaemias, late recurrent infections, new infections and coinfections indicated that the pathogenic role of this species should be carefully reconsidered. Surprisingly, we observed that by comparing the incidence of isolation of the IVD-related BSI causative yeasts with the general incidence of the species isolated in both the blood and in the IVD, our study showed that the isolation of C. albicans in the blood is associated with a lower relative risk of being IVD-associated.…”
Section: Discussionmentioning
confidence: 92%
“…Indeed, in our study C. parapsilosis complex was the species most frequently isolated in IVD-related candidaemia, both in the ICU and in the surgical wards, and the relationship with the biofilm production of these strains was investigated very recently [28]. Therefore, despite the fact that C. parapsilosis complex has long been considered to be a low-virulence species [29], our observation that C. parapsilosis complex was the main species involved in IVD-related candidaemias, late recurrent infections, new infections and coinfections indicated that the pathogenic role of this species should be carefully reconsidered. Surprisingly, we observed that by comparing the incidence of isolation of the IVD-related BSI causative yeasts with the general incidence of the species isolated in both the blood and in the IVD, our study showed that the isolation of C. albicans in the blood is associated with a lower relative risk of being IVD-associated.…”
Section: Discussionmentioning
confidence: 92%
“…Risk factors for candida bloodstream infections include colonisation with the organism in other body sites associated with the presence of intravascular catheters. Carriage of the infecting strain on the hands of health-care workers may also cause nosocomial infections [22]. In patients who have candidaemia, the same species may be isolated from specimens other than blood cultures at the same time (within 1 week), and colonisation of different body sites may be the first sign of a systemic candida infection.…”
Section: Discussionmentioning
confidence: 99%
“…Candida albicans is the main causative agent of oropharyngeal candidiasis, while the clinical significance of other non-C. albicans species such as Candida parapsilosis and Candida krusei are being increasingly recognized (16,24,28). The first step in the pathogenesis of candidal infection entails the adhesion of the yeast to the host surface or an associated prostheses, such as a denture or intravascular catheter material (18,27,34).…”
mentioning
confidence: 99%