2021
DOI: 10.1096/fj.202100263r View full text |Buy / Rent full text
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Abstract: We tested the hypothesis that cancer cachexia progression would induce oxidative post‐translational modifications (Ox‐PTMs) associated with skeletal muscle wasting, with different responses in muscles with the prevalence of glycolytic and oxidative fibers. We used cysteine‐specific isotopic coded affinity tags (OxICAT) and gel‐free mass spectrometry analysis to investigate the cysteine Ox‐PTMs profile in the proteome of both plantaris (glycolytic) and soleus (oxidative) muscles in tumor‐bearing and control rat… Show more

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