volume 50, issue 1, P49-53 1998
DOI: 10.1016/s0306-9877(98)90177-3
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Abstract: The presence of benign proliferative lesions is a risk factor for the development of cancer. However, only a subset of individuals presenting with benign lesions goes on to develop cancer. It is a major challenge of cancer research to identify those individuals at increased risk for this neoplastic progression. It has been suggested that individuals with inherent genomic instability may have a predisposition for cancer development. The hypothesis is presented that this genetic instability could be quantified t…

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