Calidad Proteica y Timo. Estudio en Modelo Experimental

Feliu, Marı́a Susana; Slobodianik, Nora

doi:10.14409/fabicib.v2i1.591

Cited by 3 publications

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“…el perfil de ácidos grasos de la dieta tiene un rol importante como regulador del sistema immune. en timo, se han observado importantes modificaciones anatómicas y funcionales en respuesta a desór-denes nutricionales, dado su rápido recam-bio celular y por esto, dicho órgano es un marcador biológico de gran utilidad y refleja en poco tiempo las alteraciones producidas por la dieta (10).…”

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Efecto De Diferentes Fuentes Y Concentraciónes De Lípidos Dietarios Sobre Suero, Timo Y Cerebro. Modelo Experimental.

Perris¹,

Fernandez²,

Mambrin³

et al. 2017

FABICIB

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Se analiza el efecto de dietas con diferente contenido en lípidos aportados por distintas fuentes alimenticias, administradas durante 10 días a ratas en período de crecimiento. Ratas Wistar al destete fueron alimentadas durante 10 días con dieta experimental conteniendo F%=15 y 42 (F%=Kcal lipídicas/100Kcal totales). Las fuentes lipídicas fueron: manteca, aceite de oliva, aceite de girasol alto oleico, aceite de girasol. La dieta control (F%15) contenía aceite de soja. Se determinaron los niveles séricos de triglicéridos, colesterol total, no-HDL colesterol- por métodos enzimáticos- y el perfil de ácidos grasos (AG) en suero, timo y cerebro por Cromatografía Gaseosa.Analizando los resultados en forma global, se demuestra que a pesar del corto tiempo de administración de las dietas, el perfil de AG en los grupos estudiados difiere del control como consecuencia del contenido de AG de las diferentes fuentes. La influencia de la alimentación sobre el perfil de ácidos grasos en los distintos órganos muestra su posible incidencia sobre ciertos factores de riesgo de enfermedades crónicas.

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Section: Trabajo Completounclassified

Efecto De Diferentes Fuentes Y Concentraciónes De Lípidos Dietarios Sobre Suero, Timo Y Cerebro. Modelo Experimental.

Perris¹,

Fernandez²,

Mambrin³

et al. 2017

FABICIB

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“…Blood samples were collected from fasting patients. Specific serum protein fractions of potential usefulness in nutrition studies: transthyretin (TTR), transferrin (Transf), C3 (C3c) and C4 complement (C4c); and acute phase serum fractions: ceruloplasmin (Cp), haptoglobin (Hapto) and protein C reactive (PCR) were measured by single radial immunodiffusion technique on agar gel layers (Biocientífica S.A., Argentina and Binding Site, UK) (2,3) . Clinical aspects were evaluated by Bioelectrical Impedance Analysis (BIA that determines electrical properties of the body resistance (R) and capacitance (Xc)); and basal metabolism (BM).…”

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confidence: 99%

Biochemical parameters in patients suffering from head and neck cancer

Feliu

Silva

Cresta³

et al. 2011

Proc. Nutr. Soc.

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The aim of the study was to evaluate the nutritional status of patients suffering from head and neck cancer at the beginning of the specific treatment, through the use of biochemical parameters (1) . Body weight (w, kg) and height (h, m) were determined, and the BMI calculated in 20 adults, who attended TRU, Angel Roffo Institute of Oncology. Blood samples were collected from fasting patients. Specific serum protein fractions of potential usefulness in nutrition studies: transthyretin (TTR), transferrin (Transf), C3 (C3c) and C4 complement (C4c); and acute phase serum fractions: ceruloplasmin (Cp), haptoglobin (Hapto) and protein C reactive (PCR) were measured by single radial immunodiffusion technique on agar gel layers (Biocientífica S.A., Argentina and Binding Site, UK) (2,3) . Clinical aspects were evaluated by Bioelectrical Impedance Analysis (BIA that determines electrical properties of the body resistance (R) and capacitance (Xc)); and basal metabolism (BM). We calculated the phase angle (arc tangent of the ratio Xc to R in degrees) that measures lean body mass (3) . Biochemical parameters (mg/dl), and BMI (kg/m 2 ) expressed as means and SD, were compared with reference values (VR). The data showed lower TTR, C3c and Transferrin together with higher Cp and Haptoglobin sera levels, than reference values. Results pointed out to a depressed nutritional status and inflammation. Besides, only 10 % showed BMI < 18.5 %. Thirty-five percent patients had reduction of phase angle and 15 % had increased of BM with increased PCR. These findings stress the importance of the inclusion of functional biochemical parameters in the periodic nutritional evaluation of these patients. This would allow an early assessment of the need for appropriate nutritional support, since 70 % of patients had normal BM and in this situation patients re-feeding is possible (1,4) ; on the other hand, patients with increased BM and phase angle (30-25 % respectively) could be a subgroup with systemic inflammatory status where re-feeding may not be useful.

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“…The DMFT index (decayed, missed and filled teeth) and its components (gingival index, bleeding sites and the presence of erosion on soft tissues) were calculated and evaluated (4) . Samples of whole blood and non-stimulated saliva were collected from fasting patients and serum transthyretin (TTR), C3c fraction (C3c) and total saliva IgA levels were determined by quantitative radial immunodiffusion on layers (The Binding Site, Birmingham, UK and Diffuplate; Biocientifica, Buenos Aires, Argentina) (5)(6)(7) . The results were (mg/l): IgA 82 (SD 41); TTR 271 (SD 177); C3c 828 (SD 380).…”

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confidence: 99%

Oral health and nutritional biochemical variables in adult patients with AIDS

Slobodianik¹,

Perris²,

Squassi

et al. 2008

Proc. Nutr. Soc.

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High prevalence of oral disease has been observed in patients with AIDS (1)(2)(3) . The aim of this preliminary study was to analyse oral health and its relationship with nutritional biochemical variables in a group of adult patients with AIDS. Twenty-eight patients between 25 and 50 years old who were HIV + were included. Dental status, gingival status and presence of mucosal alterations were determined. The DMFT index (decayed, missed and filled teeth) and its components (gingival index, bleeding sites and the presence of erosion on soft tissues) were calculated and evaluated (4) . Samples of whole blood and non-stimulated saliva were collected from fasting patients and serum transthyretin (TTR), C3c fraction (C3c) and total saliva IgA levels were determined by quantitative radial immunodiffusion on layers (The Binding Site, Birmingham, UK and Diffuplate; Biocientifica, Buenos Aires, Argentina) (5-7) . The results were (mg/l): IgA 82 (SD 41); TTR 271 (SD 177); C3c 828 (SD 380). When results were compared with reference values (227 (SD 74), 337 (SD 92) and 1350 (SD 270) respectively) a reduction in levels was observed. Moreover, also observed were: (a) a negative correlation between the D component of DMFT and the number of bleeding sites and TTR levels (r -0.68, P < 0.001); (b) a positive correlation between the presence of lesions on soft tissues and the concentration of total IgA in saliva (r 0.84, P < 0.001). No correlation between gingival index and biochemical variables was observed. The results suggest a compromised nutritional status concomitant with alterations in oral health in the study group.

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Calidad Proteica y Timo. Estudio en Modelo Experimental

Cited by 3 publications

References 0 publications

Efecto De Diferentes Fuentes Y Concentraciónes De Lípidos Dietarios Sobre Suero, Timo Y Cerebro. Modelo Experimental.

Efecto De Diferentes Fuentes Y Concentraciónes De Lípidos Dietarios Sobre Suero, Timo Y Cerebro. Modelo Experimental.

Biochemical parameters in patients suffering from head and neck cancer

Oral health and nutritional biochemical variables in adult patients with AIDS

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