Naibedya Chattopadhyay, Araceli Espinosa‐Jeffrey, Jacob Tfelt‐Hansen, Shozo Yano, Sanghamitra Bandyopadhyay, Edward M. Brown, Jean de Vellis
Abstract:Oligodendrocytes develop from oligodendrocyte progenitor cells (OPCs), which in turn arise from a subset of neuroepithelial precursor cells during midneurogenesis. Development of the oligodendrocyte lineage involves a plethora of cell-intrinsic and -extrinsic signals. A cell surface calcium-sensing receptor (CaR) has been shown to be functionally expressed in immature oligodendrocytes. Here, we investigated the expression and function of the CaR during oligodendrocyte development. We show that the order of CaR…
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