J. Neurosci. Res. volume 86, issue 10, P2159-2167 2008 DOI: 10.1002/jnr.21662 View full text
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Naibedya Chattopadhyay, Araceli Espinosa‐Jeffrey, Jacob Tfelt‐Hansen, Shozo Yano, Sanghamitra Bandyopadhyay, Edward M. Brown, Jean de Vellis

Abstract: Oligodendrocytes develop from oligodendrocyte progenitor cells (OPCs), which in turn arise from a subset of neuroepithelial precursor cells during midneurogenesis. Development of the oligodendrocyte lineage involves a plethora of cell-intrinsic and -extrinsic signals. A cell surface calcium-sensing receptor (CaR) has been shown to be functionally expressed in immature oligodendrocytes. Here, we investigated the expression and function of the CaR during oligodendrocyte development. We show that the order of CaR…

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