1984
DOI: 10.1055/s-2007-1023401 View full text |Buy / Rent full text
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Abstract: A 20-year-old woman required urgent replacement of a calcified prosthetic mitral porcine xenograft with a mechanical one during the 32nd week of pregnancy. Five weeks later the patient delivered a normal child. Following delivery the patient refused oral anticoagulant treatment and 7 months later she underwent emergency removal of a prosthetic valve thrombus. Six months later, still refusing anticoagulant treatment, she died of cerebral embolization. We suggest that the replacement of a degenerated biologic va… Show more

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“…Em nossos dados, nos dois casos de óbito registrados entre essas pacientes, ambos estiveram relacionados ao tromboembolismo. A gravidez pode propiciar disfunção de prótese biológica (calcificação precoce) supostamente em virtude do aumento do "turnover" de cálcio, para atender as necessidades do feto em crescimento, sendo a calcificação e rotura da válvula biológica acelerada em pacientes jovens, principalmente em adolescentes ou que implantaram a prótese na adolescência 6,12,20,21 . Verificou-se que nos dois casos de óbito registrados entre essas pacientes, um esteve relacionado à calcificação e o outro à estenose com rotura da prótese.…”
Section: Discussionunclassified
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“…Em nossos dados, nos dois casos de óbito registrados entre essas pacientes, ambos estiveram relacionados ao tromboembolismo. A gravidez pode propiciar disfunção de prótese biológica (calcificação precoce) supostamente em virtude do aumento do "turnover" de cálcio, para atender as necessidades do feto em crescimento, sendo a calcificação e rotura da válvula biológica acelerada em pacientes jovens, principalmente em adolescentes ou que implantaram a prótese na adolescência 6,12,20,21 . Verificou-se que nos dois casos de óbito registrados entre essas pacientes, um esteve relacionado à calcificação e o outro à estenose com rotura da prótese.…”
Section: Discussionunclassified