Calbindin D-28K and NADPH-diaphorase activity are localized in different populations of periglomerular cells in the rat olfactory bulb

Alonso, J.R.; Arévalo, R.; Porteros, A.; Briñón, Jesús G.; Lara, Juan M.; Aijón, José

doi:10.1016/0891-0618(93)90002-l

Cited by 51 publications

(47 citation statements)

References 26 publications

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“…Contrary to what has been reported in macrosmatic animals, in which only a spatially segregated subpopulation of olfactory fibers and glomeruli demonstrated ND staining (Scott et al, 1987;Croul-Ottman and Brunjes, 1988;Davis, 1991;Vincent and Kimura, 1992;Kishimoto et al, 1993;Alonso et al, 1993Alonso et al, , 1995bHopkins et al, 1996), all olfactory fibers and glomeruli were NDactive in the three species of macaque monkeys, Macaca fascicularis, Macaca fuscata, and Macaca nemestrina. The distribution and morphological characteristics of centrifu- gal fibers is similar in the macaque monkey OB to previous reports in rodents (Davis, 1991), although the dense ND-active neuropile described surrounding the granule cells (Davis, 1991) is not present in our preparations.…”

Section: Interspecies Differences In the Nd/nos Stainingcontrasting

confidence: 84%

“…The enzyme NADPHdiaphorase (ND) is a selective histochemical marker for distinct neuronal populations throughout the brain (Scott et al, 1987;Villalba et al, 1988Villalba et al, , 1989Mizukawa et al, 1989;Bredt et al, 1991a;Davis, 1991;Vincent and Kimura, 1992;Kishimoto et al, 1993;Alonso et al, 1993Alonso et al, , 1995aHopkins et al, 1996;Briñ ón et al, 1997;among others). After being purified and molecularly cloned from brain, neuronal nitric oxide synthase (NOS) has been found in discrete neuronal populations in the rodent and primate brains, and its localization is coincident with ND staining in both groups of mammals after aldehyde fixation (Bredt et al, 1991a).…”

Section: Indexing Terms: Histochemistry; Immunohistochemistry; Olfactmentioning

confidence: 97%

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Chemical anatomy of the Macaque monkey olfactory bulb: NADPH-diaphorase/nitric oxide synthase activity

et al. 1998

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The distribution and the morphology of nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase (ND)-active and neuronal nitric oxide synthase (NOS)-immunoreactive neurons and fibers were studied in the olfactory bulb of three species of primates, i.e., the cynomolgus macaque monkey (Macaca fascicularis), the Japanese macaque monkey (Macaca fuscata), and the pig-tail macaque monkey (Macaca nemestrina). The ND staining was carried out by means of a direct histochemical method with ␤-NADPH as cosubstrate and nitro blue tetrazolium as chromogen. The NOS immunostaining was carried out by using a polyclonal antibody and the avidin-biotin peroxidase method. Similar results were found in the three species, where a distinct distribution pattern of ND/NOS-stained neurons and fibers was observed. All olfactory fibers demonstrated ND-positive labeling but they were NOSimmunonegative. In the superficial modulatory area of the olfactory bulb, a few weakly NDand NOS-positive periglomerular cells, stellate cells, and darkly stained superficial shortaxon cells were observed. In the inframitral layers, granule cells, deep stellate cells, and deep short-axon cells were distinguished. Short-axon cells had oriented morphologies and spiny dendrites. Many thick, varicose ND/NOS-stained fibers identified as centrifugal fibers were observed in the white matter, granule cell layer, internal plexiform layer, mitral cell layer, and external plexiform layer. This distribution of ND activity and NOS immunoreactivity showed similarities to and differences from what has been reported in the olfactory bulb of macrosmatic mammals including rodents (rat, mouse, and hamster) and insectivores (hedgehog). These data confirm that the complexity of the ND/NOS staining in the olfactory bulb of one species correlates with the importance of olfaction in the biology of such species.

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Section: Interspecies Differences In the Nd/nos Stainingcontrasting

confidence: 84%

Section: Indexing Terms: Histochemistry; Immunohistochemistry; Olfactmentioning

confidence: 97%

Chemical anatomy of the Macaque monkey olfactory bulb: NADPH-diaphorase/nitric oxide synthase activity

et al. 1998

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“…As in amphibians, diversity exists with regard to the presence of CR in bulbar cells of fish because both interneurons and mitral cells contain CR in lampreys [Pombal et al, 2002] and some teleosts [Porteros et al, 1997;Díaz-Regueira and Anadón, 2000], whereas only scarce CRir interneurons were demonstrated in a chondostrean fish [Huesa et al, 2006] and no CRir cells were detected in the zebrafish and catfish olfactory bulbs [Castro et al, 2006;Jadhao and Malz, 2007]. The numerous studies conducted in different mammalian species also show enormous diversity in the content of CB and CR in bulbar cell populations [Alonso et al, 1993[Alonso et al, , 1995Malz et al, 2000;Jia and Halpern, 2004;Parrish-Aungst et al, 2007]. However, it is a shared feature that the periglomerular cells are always rich in CB and CR [Briñón et al, 1992;Alonso et al, 1993;Toida et al, 1998;Kakuta et al, 2001;Jia and Halpern, 2004;Kosaka and Kosaka, 2007], whereas species differences exist regarding the localization of these proteins in granule cells [Kakuta et al, 2001;Jia and Halpern, 2004].…”

Section: Olfactory Bulbsmentioning

confidence: 99%

“…The numerous studies conducted in different mammalian species also show enormous diversity in the content of CB and CR in bulbar cell populations [Alonso et al, 1993[Alonso et al, , 1995Malz et al, 2000;Jia and Halpern, 2004;Parrish-Aungst et al, 2007]. However, it is a shared feature that the periglomerular cells are always rich in CB and CR [Briñón et al, 1992;Alonso et al, 1993;Toida et al, 1998;Kakuta et al, 2001;Jia and Halpern, 2004;Kosaka and Kosaka, 2007], whereas species differences exist regarding the localization of these proteins in granule cells [Kakuta et al, 2001;Jia and Halpern, 2004].…”

Section: Olfactory Bulbsmentioning

confidence: 99%

Localization of Calbindin-D28k and Calretinin in the Brain of Dermophis Mexicanus (Amphibia: Gymnophiona) and Its Bearing on the Interpretation of Newly Recognized Neuroanatomical Regions

Morona¹,

López²,

González³

2011

Brain Behav Evol

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The analysis of the distribution of the calbindin-D28k and calretinin immunoreactive (CBir and CRir) systems recently described in the brain of anuran and urodele amphibians was very useful for the interpretation of many otherwise indistinct brain regions and cell masses. In the present study we have followed a similar approach to investigate the distribution of CBir and CRir cell bodies and fibers in the brain of Dermophis mexicanus, a member of the much neglected third amphibian order of gymnophionans. The pattern of distribution obtained showed particular characteristics in Dermophis, such as the existence of abundant CRir elements in the olfactory bulbs and CBir and CRir cell populations in pallial areas. The distinct distribution of the two proteins allowed the tentative identification of currently described subregions, mainly in the amygdaloid complex and hypothalamic areas. The analysis of the diencephalon and brainstem distribution framed in the neuromeric model highlighted common traits with other amphibians but also specific features. Therefore, the immunohistochemical detection of calcium-binding proteins has served to discern cell populations and has helped to demonstrate neuronal heterogeneity. However, it should be pointed out that a straightforward comparison based only on the presence of these proteins should not be made due to the great variability observed in well-established homologous regions in the brain of different vertebrates, as evidenced within the class Amphibia.

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“…Among these cells, the periglomerular cells are very important role in odor decoding because these cells modulate the glomerular processing [1,5,13,15].…”

mentioning

confidence: 99%

Age-Related Changes in Calretinin-Immunoreactive Periglomerular Cells in the Rat Main Olfactory Bulb

Hwang

Yoo

Nam

et al. 2006

The Journal of Veterinary Medical Science

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ABSTRACT. The changes of calretinin (CR)-immunoreactive periglomerular cells in the glomerular layer of the main olfactory bulb (MOB) were investigated in rats differing ages from postnatal month 1 (PM 1) to PM 24. The number of cresyl violet-positive periglomerular cells was similar between PM 1 and PM 12, but they decreased slightly in the PM 24 group. The size of CR-immunoreactive periglomerular cells in the glomerular layer increased with age, while their numbers did not change significantly in the PM 6-PM 24 groups. In the PM 24 group, numbers of CR-positive periglomerular cell bodies and their processes decreased, while the size of CR-positive cell bodies in the glomeruli was larger than that of the previous groups. These results suggest that CR-immunoreactive periglomerular cells in the rat MOB are well-developed in the PM 6 group, and that periglomerular cells in the PM 24 group show poor CR-immunoreactivity compared to those in the PM 6 group.

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Calbindin D-28K and NADPH-diaphorase activity are localized in different populations of periglomerular cells in the rat olfactory bulb

Cited by 51 publications

References 26 publications

Chemical anatomy of the Macaque monkey olfactory bulb: NADPH-diaphorase/nitric oxide synthase activity

Chemical anatomy of the Macaque monkey olfactory bulb: NADPH-diaphorase/nitric oxide synthase activity

Localization of Calbindin-D28k and Calretinin in the Brain of Dermophis Mexicanus (Amphibia: Gymnophiona) and Its Bearing on the Interpretation of Newly Recognized Neuroanatomical Regions

Age-Related Changes in Calretinin-Immunoreactive Periglomerular Cells in the Rat Main Olfactory Bulb

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