Cages on Surfaces: Thiol Functionalisation of Co^III Sarcophagine Complexes

The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals

“…Several metallic isotopes have desirable properties for use in PET including 68 Ga and 94m Tc. There are also copper isotopes that are of interest namely, 60 Cu, 61 Cu, 62 Cu and 64 Cu that are all positron emitters. 4 The half-life of these copper isotopes range from relatively short (9.74 m for 62 Cu) to relatively long (12.7 h for 64 Cu).…”

“…There are also copper isotopes that are of interest namely, 60 Cu, 61 Cu, 62 Cu and 64 Cu that are all positron emitters. 4 The half-life of these copper isotopes range from relatively short (9.74 m for 62 Cu) to relatively long (12.7 h for 64 Cu). The long half-life of the latter allows PET imaging to be carried out at a site remote from the cyclotron facility used to generate the radionuclide.…”

“…The long half-life of the latter allows PET imaging to be carried out at a site remote from the cyclotron facility used to generate the radionuclide. In addition to the PET imaging capabilities of 64 Cu this radionuclide also has a bemission that is suitable for certain therapeutic applications. The bemitting 67 Cu isotope has a 72 h half-life and also has potential in radiotherapeutic applications.…”

Spectroelectrochemical Properties and Catalytic Activity in Cyclohexane Oxidation of the Hybrid Zr/Hf-Phthalocyaninate-Capped Nickel(II) and Iron(II) tris-Pyridineoximates and Their Precursors

“…On the other hand, the designed d -metal clathrochelates were reported [ 47 , 48 , 49 ] to be useful for protein sensing or efficient electro- and (pre)catalysts for hydrogen and syngas (H 2 + CO) production. A series of the polyamine cobalt(III) cage complexes with tethered mercaptoethylamide terminated oligopeptide apical substituents, allowing for immobilization on a surface of the working gold electrode, was described [ 50 ] to be potent heterogeneous electrocatalysts in both the hydrogen evaluation reaction (HER) and the oxygen reduction to hydrogen peroxide. Photodissociation of water was realized on rhodium-doped strontium titanate photoelectrode surface modified by a cobalt(II) clathrochelate when using methanol as a sacrificial agent [ 51 ].…”

Synthesis and characterization of an amphiphilic cobalt cage complex with aza-crown spacer

“…Foremost, is the preservation of chromophore and redox characteristics of the metal in a range of chemical environments [3,4] and the associated potential for applications as inert but easily detectable molecular sensors [5], electron transfer agents [6,7] and radiopharmaceuticals [8,9]. If the amine cage is functionalized with lipophilic pendant groups [10-12], the resulting amphiphiles have added surfactant, catalytic and biological activity capabilities [13][14][15]. As part of our interest in delineating structure activity relationships in mesophases and membrane transport processes, we have synthesized and herein report the properties of the first example of a [Co(sar)] 3+ derivative which combines a lipophilic tail and an aza-crown ether spacer group for the investigation of ionic transport across cell membranes.…”