Caffeine-Related Atrial Fibrillation

Artin, Bassel; Singh, Mukesh; Richeh, Chadi; Jawad, Evyan; Arora, Rohit; Khosla, Sandeep

doi:10.1097/mjt.0b013e3181df8cf8

Cited by 24 publications

(12 citation statements)

References 8 publications

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“…Most deaths after caffeine intoxication were caused by overdoses of diet pills and stimulants, and most have occurred in young patients without known underlying heart disease or any variant of normal, such as mitral valve prolapse. In one non-fatal adverse event report, no predisposing factors or structural cardiac abnormality were associated with atrial fibrillation (122). In this case, caffeine-induced atrial fibrillation spontaneously reverted to normal sinus rhythm.…”

Section: Caffeine Toxicitymentioning

confidence: 99%

The Safety of Ingested Caffeine: A Comprehensive Review

Temple¹,

Bernard²,

Lipshultz³

et al. 2017

Front. Psychiatry

362

254

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Caffeine is the most widely consumed psychoactive drug in the world. Natural sources of caffeine include coffee, tea, and chocolate. Synthetic caffeine is also added to products to promote arousal, alertness, energy, and elevated mood. Over the past decade, the introduction of new caffeine-containing food products, as well as changes in consumption patterns of the more traditional sources of caffeine, has increased scrutiny by health authorities and regulatory bodies about the overall consumption of caffeine and its potential cumulative effects on behavior and physiology. Of particular concern is the rate of caffeine intake among populations potentially vulnerable to the negative effects of caffeine consumption: pregnant and lactating women, children and adolescents, young adults, and people with underlying heart or other health conditions, such as mental illness. Here, we review the research into the safety and safe doses of ingested caffeine in healthy and in vulnerable populations. We report that, for healthy adults, caffeine consumption is relatively safe, but that for some vulnerable populations, caffeine consumption could be harmful, including impairments in cardiovascular function, sleep, and substance use. We also identified several gaps in the literature on which we based recommendations for the future of caffeine research.

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Section: Caffeine Toxicitymentioning

confidence: 99%

The Safety of Ingested Caffeine: A Comprehensive Review

Temple¹,

Bernard²,

Lipshultz³

et al. 2017

Front. Psychiatry

362

254

View full text Add to dashboard Cite

show abstract

“…Anecdotal evidence points to caffeine consumption as a trigger of AF22, 48, 49 but observational studies have had conflicting results. Results of observational studies exploring this association are summarized in Table 3.…”

Section: Caffeine Intake and Afmentioning

confidence: 99%

Diet and Risk of Atrial Fibrillation - Epidemiologic and Clinical Evidence -

Gronroos

Alonso

2010

Circ J

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Dietary factors might affect the risk of atrial fibrillation (AF), but available studies have provided inconsistent results. A review of published observational studies and randomized trials identified 4 dietary exposures that had been investigated regarding AF risk: alcohol, fish-derived n-3 polyunsaturated fatty acids, caffeine, and ascorbic acid. Though studies were highly heterogeneous in their design and results, they showed a consistently increased risk of AF in heavy alcohol drinkers, but no risk associated with moderate alcohol intake. High coffee intake was not clearly associated with an increased risk of AF, and a potential U-shaped association (lower AF risk in moderate drinkers) could exist. High intake of fish-derived n-3 polyunsaturated fatty acids from diet or supplements might prevent AF episodes following cardiovascular events, but no consistent evidence supports an effect in primary prevention. Additional large, well-conducted randomized experiments are necessary to address the role of diet in AF prevention. (Circ J 2010; 74: 2029 - 2038

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“…The association between caffeine exposure and AF is currently unknown, although a positive association has been suggested in the literature 14 15. To further evaluate this putative association, we performed a systematic review and meta-analysis of observational studies.…”

Section: Introductionmentioning

confidence: 99%