volume 2, issue 8, PS384-S385 2007
DOI: 10.1097/01.jto.0000283241.14454.e3
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Abstract: Background: Cell cycle checkpoint function is crucial for the prevention of carcinogenesis in mammalian cells. To test the hypothesis that common sequence variants of genes in the cell cycle control pathway may affect lung cancer predisposition, we explored the associations of 11 polymorphisms in seven cell cycle control genes with lung cancer risk. Methods: We conducted a case-control study in Caucasians that included 1,518 lung cancer patients and 1,518 controls. Results: Our results showed that when individ…

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