volume 2, issue 8, PS375-S376 2007
DOI: 10.1097/01.jto.0000283224.56144.7b
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Abstract: to the A&C regimen. Tumors were resected prior to drug treatment and their RNAs analyzed using the microarray Affymetrix platforms followed by the unsupervised cluster analysis. Genes-discriminators were then validated by RT-PCR on tumor and normal tissue-matched clinical samples. Results. We found a clear segregation of drug responsive vs. drug resistant patients based on the analysis of differentially expressed genes. SLC39A8, PMCA1, and PLCB1 were identified as the most robust discriminators of these two gr…

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