2012
DOI: 10.1016/j.biortech.2012.07.104
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Butanol production from renewable biomass by clostridia

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Cited by 254 publications
(139 citation statements)
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“…It can be produced from the fermentation of the sugars in biomass. Recently, the use of genetically enhanced bacteria increased the fermentation process productivity [5], [6]. It is expected that a sustainable and cost effective process for butanol production will be realized in the foreseeable future.…”
Section: Introductionmentioning
confidence: 99%
“…It can be produced from the fermentation of the sugars in biomass. Recently, the use of genetically enhanced bacteria increased the fermentation process productivity [5], [6]. It is expected that a sustainable and cost effective process for butanol production will be realized in the foreseeable future.…”
Section: Introductionmentioning
confidence: 99%
“…Although Clostridium can naturally produce isopropanol and butanol, it is a strict anaerobe with a spore-forming life cycle characterized by a slow growth rate (Jones and Woods 1986;Zheng et al 2009;Green 2011;Jang et al 2012). In addition, limited genetic tools were available to engineer solvent production in this organism (Branduardi et al 2014).…”
Section: Genetic Engineering Of Clostridia For Enhanced Butanol and Imentioning
confidence: 99%
“…Finally, the status of commercialization of some of the advanced biofuels compared to bioethanol, potential research avenues, and the future perspectives for their commercial success are discussed. In ABE/IBE fermentation, after glycolysis, pyruvate is converted to acetyl-CoA by the enzyme pyruvate ferredoxin oxidoreductases (Ezeji et al 2007;Fischer et al 2008;Zheng et al 2009;Jang et al 2012). Subsequently, two acetyl-CoA molecules undergo Claisen condensation to form acetoacetyl-CoA, which is reduced to 3-hydroxybutyryl-CoA, then dehydrated to form crotonyl-CoA and further reduced to butyryl-CoA, butyraldehyde, and finally butanol ( Fig.…”
Section: Introductionmentioning
confidence: 99%
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“…The main limitation of producing bio-butanol on a large scale is that the separation process of butanol from the ABE fermentation products requires extra energy consumption and thus increases manufacturing costs [17][18][19][20][21]. This issue has prompted researchers' interests in the possibility of…”
Section: Introductionmentioning
confidence: 99%