Buprenorphine for the management of opioid withdrawal

Comparison of Buprenorphine and Methadone in the Treatment of Opiate Withdrawal

“…16,17 The present results are consistent with findings from other studies that have found some superiority of buprenorphine over methadone detoxification. 8,11 Detoxification with buprenorphine plus carbamazepine has been shown to be superior to methadone plus carbamazepine. 18 Other studies have reported buprenorphine and methadone to be of comparable effectiveness.…”

“…Buprenorphine, prescribed in reducing doses, has been found to be more effective than adrenergic agonists in alleviating opiate withdrawal symptoms 8 and of broadly comparable effectiveness to methadone. 9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone.…”

“…9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone. 8 The present study is a preliminary investigation of the effectiveness of buprenorphine and methadone as detoxification treatments for opiate-dependent inpatients. Study limitations include the use of an open-label design and nonrandom assignment of patients.…”

Comparison of Buprenorphine and Methadone in the Treatment of Opiate Withdrawal

“…16,17 The present results are consistent with findings from other studies that have found some superiority of buprenorphine over methadone detoxification. 8,11 Detoxification with buprenorphine plus carbamazepine has been shown to be superior to methadone plus carbamazepine. 18 Other studies have reported buprenorphine and methadone to be of comparable effectiveness.…”

“…Buprenorphine, prescribed in reducing doses, has been found to be more effective than adrenergic agonists in alleviating opiate withdrawal symptoms 8 and of broadly comparable effectiveness to methadone. 9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone.…”

“…9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone. 8 The present study is a preliminary investigation of the effectiveness of buprenorphine and methadone as detoxification treatments for opiate-dependent inpatients. Study limitations include the use of an open-label design and nonrandom assignment of patients.…”

Prevention of HIV Infection among Injection Drug Users in Resource‐Limited Settings

“…The consistency of findings from randomized trials and observational studies provides compelling evidence that OAT is significantly associated with reduced HIV risk behaviors, including decreased injection frequency and lower rates of HIV seroconversion [69–72]. Some studies have also shown that OAT is associated with decreased sharing of injection equipment and reductions in unprotected sex [73–75].…”

Comparison of Buprenorphine and Methadone in the Treatment of Opiate Withdrawal

“…16,17 The present results are consistent with findings from other studies that have found some superiority of buprenorphine over methadone detoxification. 8,11 Detoxification with buprenorphine plus carbamazepine has been shown to be superior to methadone plus carbamazepine. 18 Other studies have reported buprenorphine and methadone to be of comparable effectiveness.…”

“…Buprenorphine, prescribed in reducing doses, has been found to be more effective than adrenergic agonists in alleviating opiate withdrawal symptoms 8 and of broadly comparable effectiveness to methadone. 9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone.…”

“…9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone. 8 The present study is a preliminary investigation of the effectiveness of buprenorphine and methadone as detoxification treatments for opiate-dependent inpatients. Study limitations include the use of an open-label design and nonrandom assignment of patients.…”

Prevention of HIV Infection among Injection Drug Users in Resource‐Limited Settings

“…The consistency of findings from randomized trials and observational studies provides compelling evidence that OAT is significantly associated with reduced HIV risk behaviors, including decreased injection frequency and lower rates of HIV seroconversion [69–72]. Some studies have also shown that OAT is associated with decreased sharing of injection equipment and reductions in unprotected sex [73–75].…”

Comparison of Buprenorphine and Methadone in the Treatment of Opiate Withdrawal

“…16,17 The present results are consistent with findings from other studies that have found some superiority of buprenorphine over methadone detoxification. 8,11 Detoxification with buprenorphine plus carbamazepine has been shown to be superior to methadone plus carbamazepine. 18 Other studies have reported buprenorphine and methadone to be of comparable effectiveness.…”

“…Buprenorphine, prescribed in reducing doses, has been found to be more effective than adrenergic agonists in alleviating opiate withdrawal symptoms 8 and of broadly comparable effectiveness to methadone. 9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone.…”

“…9,10 Better treatment retention has been found among patients treated with buprenorphine than with methadone, 11 and opiate withdrawal symptoms may resolve more rapidly after treatment with buprenorphine than with methadone. 8 The present study is a preliminary investigation of the effectiveness of buprenorphine and methadone as detoxification treatments for opiate-dependent inpatients. Study limitations include the use of an open-label design and nonrandom assignment of patients.…”

Prevention of HIV Infection among Injection Drug Users in Resource‐Limited Settings

“…The consistency of findings from randomized trials and observational studies provides compelling evidence that OAT is significantly associated with reduced HIV risk behaviors, including decreased injection frequency and lower rates of HIV seroconversion [69–72]. Some studies have also shown that OAT is associated with decreased sharing of injection equipment and reductions in unprotected sex [73–75].…”