Bullous sclerodermalike changes in chronic graft-vs-host disease

Skin ulcers related to chronic graft-versus-host disease: clinical findings and associated morbidity

“…Skin ulcers appeared because of bullous lichenoid lesions or bullous morphoea and not because of traumatic causes. Bullous lichenoid lesions and bullous morphoea have already been described in the setting of cGVHD and cause a detachment between the epidermis and the dermis leading to skin erosion. In bullous morphoea, biopsy findings generally reveal thickened sclerotic deeply eosinophilic collagen bundles that extend to subcutaneous tissue or at the level of deep reticular dermis, subepidermal blisters, variable subepidermal oedema, lymphatic dilatation, and moderate inflammatory infiltration around the blood vessels.…”

Bullous scleroderma‐like changes in chronic graft‐versus‐host disease

“…Recently we treated a patient with these alterations. To the best of our knowledge this is the second case described 4 in the literature.…”