1984
DOI: 10.1001/archderm.120.9.1196
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Bullous pemphigoid-like lesions induced by phenacetin. Report of a case and an immunopathologic study

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Cited by 25 publications
(14 citation statements)
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“…Descriptions of cases of this form of bullous pempbigoid are more and more frequently reported in literature. The characteristics they seem to show, with respect to idiopathic pemphigoid, are the following: 1) more frequent occurrence on the face and absence of erythema; 2) often of short, self-limited course [1,[8][9][10][11][12]; 3) a lower average age of onset [13]; 4) non diagnostic histological findings [2]; 5) possible absence of anti-basement membrane zone (BMZ) IgG antibodies in direct and indirect immunofluorescence [11]; 6) in some cases, however, there are other autoantibodies such as intercellular [14] or anticytoplasmic [10].…”
Section: Discussionmentioning
confidence: 99%
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“…Descriptions of cases of this form of bullous pempbigoid are more and more frequently reported in literature. The characteristics they seem to show, with respect to idiopathic pemphigoid, are the following: 1) more frequent occurrence on the face and absence of erythema; 2) often of short, self-limited course [1,[8][9][10][11][12]; 3) a lower average age of onset [13]; 4) non diagnostic histological findings [2]; 5) possible absence of anti-basement membrane zone (BMZ) IgG antibodies in direct and indirect immunofluorescence [11]; 6) in some cases, however, there are other autoantibodies such as intercellular [14] or anticytoplasmic [10].…”
Section: Discussionmentioning
confidence: 99%
“…In one case of bullous pemphigoid induced by phenacetin, immunoelectronmicroscopic studies showed that the antigenic sites for the autoantibodies were partially different from those found in idiopathic bullous pemphigoid [10];…”
Section: Etiopathogenetic Mechanismsmentioning
confidence: 90%
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“…Systemic and topical drugs reported to have triggered BP include frusemide, penicillamine, penicillin and its derivatives, angiotensin‐converting enzyme inhibitors such as captopril and enalapril, nalidixic acid, salicylazosulphapyridine, ibuprofen, phenacetin, topical fluorouracil and psoralen‐ultraviolet A (PUVA) therapy. 4–6 …”
mentioning
confidence: 99%
“…later suggested that drugs may structurally modify molecules and uncover hidden epitopes, thereby stimulating an autoimmune response. 4 Many drugs which trigger BP contain sulphur or sulphydryl groups, e.g. penicillamine, captopril and frusemide.…”
mentioning
confidence: 99%