Bullous Keratogenous and Pigmentary Dermatitis With Blood Eosinophilia in Newborn Girls

The Genetics of Incontinentia Pigmenti

“…There are several other reports of cases with apparently unaffected parents but af¬ fected sisters (Calnan,9 Jackson and Nigam,10 Teik et al,11 Rozehnahl et al12) and one instance of two girls and one boy (Pinkus13). In one family (Michel and Saint Paul14), it is doubtful if the severe malformations of four male and female siblings of the female proband were due to incontinentia pigmenti.…”

Incontinentia pigmenti in a newborn boy.

“…It is thus often associated with malformations of the bones, teeth, sensory organs and the central nervous system. Such malformations are occasionally seen in other members of the family without any signs of skin disorders (3). In 1966, Curth (s) collected 216 cases of the disease from the literature, of which only 12 had occurred in males.…”