Bullous Eruptions in Hemorrhagic Sarcoma of Kaposi and in Lichen Planus

Wise, Fred

doi:10.1001/archderm.1923.02360110054009

Cited by 8 publications

(1 citation statement)

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“…Only a few specific reports and case presentations that described this type of variant of KS were found, most of which were not reported in the English literature. In these reports skin lesions were described variously as “plaques of distended, compressible skin,”“cystic tumors,” and “isolated fused vesicles and bullae in infiltrated skin areas.” 14–26 Ronchese and Kern 9 thought that the lymphomatous nature of the tumor resulted from a lymphatic obstruction by the neoplasm. However, in the discussion following the paper, several discussants disagreed and felt the lymphangioma‐like lesions originated from the primary neoplastic process.…”

Section: Discussionmentioning

confidence: 99%

A Bullous Variant of Kaposi's Sarcoma in an Elderly Female

Recht

Nickoloff

Wood

1986

The Journal of Dermatologic Surgery and Oncology

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We report the case of Kaposi's Sarcoma (KS) in an elderly Italian female that has slowly progressed and evolved clinically with bullous formation. The skin biopsy was diagnostic of KS, showing the typical spindle cell formations, but at the same time showing a labyrinth-like collection of vessels that correlated with the bullous nature of the clinical lesions. Immunohistochemical staining for factor VIII antigens demonstrated strong reactivity of non-neoplastic blood vessel endothelium but virtually no staining of tumor cells. This is similar to the reactivity of normal lymphatic endothelial cells and supports the notion that these labyrinth-like vessels are derived from lymphatic endothelium.

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Section: Discussionmentioning

confidence: 99%