Bullous Darier's disease

Vesicular Darier’s disease: a case report and review of the English literature of a rare disease variant

“…A comprehensive literature search was performed, which revealed a total of 26 case reports that described cases of vesicular Darier’s disease via search of title and/or abstract. 3 – 28 A list of 16 case reports that were accessible in English is summarized in Table 1 .…”

A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder

“…Only ten cases of the vesiculo-bullous variant of Darier's disease have been reported in the literature of the last thirty years (13)(14)(15)(16)(17). Such a variant is usually due to an increase in suprabasal acantholysis demonstrable by light microscopy in the characteristic keratotic papules.…”

“…After the first case reported by]ablonska et al in 1958~(13), only anecdotal ones have been reported in the literature. In 1969, Reed et al described a 34-year-old female with generalized Darier's disease who subsequently developed, in summer, bullous lesions on photoexposed areas (14). In 1982, Hori et al described a similar case that also developed in summer (15).…”

“…Clinically, Darier's disease is characterized by small isolated papules that usually appear in childhood or in the teens (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) . years of age).…”

The Surgical Treatment of Hypertrophic Darier's Disease

“…Unusual reported variants of Darier's disease include a bullous type, 10–13 a zosteriform or linear type, 14,15 a unilateral type, 16 and, perhaps the most severe, a widespread hypertrophic type 17–20 . In this type, the lesions become markedly thickened and hyperkeratotic, resulting in the development of wartlike masses and plaques.…”