Budesonide for maintenance of remission in Crohn's disease

Review article: the evidence base for interventions used to maintain remission in Crohn’s disease

“…Three RCTs on 270 patients whose disease was restricted to the ileum and right colon were included in the review on budesonide 9 . There was no statistically significant difference between budesonide 6 mg/day and placebo for prevention of relapse of CD over 12 months (Relative risk 0.89, 95% CI 0.71 to1.13).…”

Review article: the evidence base for interventions used to maintain remission in Crohn’s disease

“…Three RCTs on 270 patients whose disease was restricted to the ileum and right colon were included in the review on budesonide 9 . There was no statistically significant difference between budesonide 6 mg/day and placebo for prevention of relapse of CD over 12 months (Relative risk 0.89, 95% CI 0.71 to1.13).…”

Clinical, endoscopic and histopathological evaluation of the efficacy of budesonide in the treatment of inflammatory bowel disease in dogs

“…Budesonide was found to be more effective than placebo in the treatment of Crohn's disease in humans, but its therapeutic efficacy was not higher in comparison with other orally administered glucocorticosteroids (Otley and Steinhart 2005). According to Cochrane Reviews, the results of clinical, macroscopic and histopathological evaluations indicate that budesonide is not more effective in maintaining remission in Crohn's disease than prednisone (Papi et al 2000, Simms andSteinhart 2001). In short-term therapy, budesonide was less effective than conventional steroids, in particular in patients with severe IBD and extensive intestinal changes (Seow et al 2008).…”

Systematic Review of the Evidence Base for the Medical Treatment of Paediatric Inflammatory Bowel Disease

“…Corticosteroid therapy is more effective than EN for remission of active CD (130). There is no evidence for using either prednisolone (131) or budesonide (132) in the maintenance of medically induced remission in CD.…”

Review article: the evidence base for interventions used to maintain remission in Crohn’s disease

“…Three RCTs on 270 patients whose disease was restricted to the ileum and right colon were included in the review on budesonide 9 . There was no statistically significant difference between budesonide 6 mg/day and placebo for prevention of relapse of CD over 12 months (Relative risk 0.89, 95% CI 0.71 to1.13).…”

Clinical, endoscopic and histopathological evaluation of the efficacy of budesonide in the treatment of inflammatory bowel disease in dogs

“…Budesonide was found to be more effective than placebo in the treatment of Crohn's disease in humans, but its therapeutic efficacy was not higher in comparison with other orally administered glucocorticosteroids (Otley and Steinhart 2005). According to Cochrane Reviews, the results of clinical, macroscopic and histopathological evaluations indicate that budesonide is not more effective in maintaining remission in Crohn's disease than prednisone (Papi et al 2000, Simms andSteinhart 2001). In short-term therapy, budesonide was less effective than conventional steroids, in particular in patients with severe IBD and extensive intestinal changes (Seow et al 2008).…”

Systematic Review of the Evidence Base for the Medical Treatment of Paediatric Inflammatory Bowel Disease

“…Corticosteroid therapy is more effective than EN for remission of active CD (130). There is no evidence for using either prednisolone (131) or budesonide (132) in the maintenance of medically induced remission in CD.…”

Review article: the evidence base for interventions used to maintain remission in Crohn’s disease

“…Three RCTs on 270 patients whose disease was restricted to the ileum and right colon were included in the review on budesonide 9 . There was no statistically significant difference between budesonide 6 mg/day and placebo for prevention of relapse of CD over 12 months (Relative risk 0.89, 95% CI 0.71 to1.13).…”

Clinical, endoscopic and histopathological evaluation of the efficacy of budesonide in the treatment of inflammatory bowel disease in dogs

“…Budesonide was found to be more effective than placebo in the treatment of Crohn's disease in humans, but its therapeutic efficacy was not higher in comparison with other orally administered glucocorticosteroids (Otley and Steinhart 2005). According to Cochrane Reviews, the results of clinical, macroscopic and histopathological evaluations indicate that budesonide is not more effective in maintaining remission in Crohn's disease than prednisone (Papi et al 2000, Simms andSteinhart 2001). In short-term therapy, budesonide was less effective than conventional steroids, in particular in patients with severe IBD and extensive intestinal changes (Seow et al 2008).…”

Systematic Review of the Evidence Base for the Medical Treatment of Paediatric Inflammatory Bowel Disease

“…Corticosteroid therapy is more effective than EN for remission of active CD (130). There is no evidence for using either prednisolone (131) or budesonide (132) in the maintenance of medically induced remission in CD.…”