Budesonide at different doses for chronic asthma

Nebulised budesonide using a novel device in patients with oral steroid-dependent asthma

“…This observation is consistent with a meta-analysis of results from trials enrolling adult patients with suboptimally controlled severe asthma treated with OCS; FEV1 and morning PEF both improved on 1600 µg per day inhaled Bud compared with 200 µg per day [28].…”

Nebulised budesonide using a novel device in patients with oral steroid-dependent asthma

“…This observation is consistent with a meta-analysis of results from trials enrolling adult patients with suboptimally controlled severe asthma treated with OCS; FEV1 and morning PEF both improved on 1600 µg per day inhaled Bud compared with 200 µg per day [28].…”

Predictive distributions were developed for the extent of heterogeneity in meta-analyses of continuous outcome data

“…As a contrasting example, we also reanalyzed data from a published meta-analysis consisting of just five studies to compare budesonide at different doses for chronic asthma ( Fig. 2 B) [15] . In a conventional random-effects meta-analysis, the heterogeneity is low but again imprecisely estimated [ τ 2 = 0 (95% CI: 0, 0.45), I 2 = 0%].…”

Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study

“…Of the seven age-treatment subgroup analyses that reported a statistically significant P value from an interaction test, two were from reviews with the same authors [39, 40]; otherwise, there was not a clear pattern of interventions, comparisons, and outcomes (Table 4). Six (6 of 7, 85.7%) were from reviews that outlined plans to conduct subgroup analyses in their methods sections.…”

Nebulised budesonide using a novel device in patients with oral steroid-dependent asthma

“…This observation is consistent with a meta-analysis of results from trials enrolling adult patients with suboptimally controlled severe asthma treated with OCS; FEV1 and morning PEF both improved on 1600 µg per day inhaled Bud compared with 200 µg per day [28].…”

Predictive distributions were developed for the extent of heterogeneity in meta-analyses of continuous outcome data

“…As a contrasting example, we also reanalyzed data from a published meta-analysis consisting of just five studies to compare budesonide at different doses for chronic asthma ( Fig. 2 B) [15] . In a conventional random-effects meta-analysis, the heterogeneity is low but again imprecisely estimated [ τ 2 = 0 (95% CI: 0, 0.45), I 2 = 0%].…”

Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study

“…Of the seven age-treatment subgroup analyses that reported a statistically significant P value from an interaction test, two were from reviews with the same authors [39, 40]; otherwise, there was not a clear pattern of interventions, comparisons, and outcomes (Table 4). Six (6 of 7, 85.7%) were from reviews that outlined plans to conduct subgroup analyses in their methods sections.…”

Nebulised budesonide using a novel device in patients with oral steroid-dependent asthma

“…This observation is consistent with a meta-analysis of results from trials enrolling adult patients with suboptimally controlled severe asthma treated with OCS; FEV1 and morning PEF both improved on 1600 µg per day inhaled Bud compared with 200 µg per day [28].…”

Predictive distributions were developed for the extent of heterogeneity in meta-analyses of continuous outcome data

“…As a contrasting example, we also reanalyzed data from a published meta-analysis consisting of just five studies to compare budesonide at different doses for chronic asthma ( Fig. 2 B) [15] . In a conventional random-effects meta-analysis, the heterogeneity is low but again imprecisely estimated [ τ 2 = 0 (95% CI: 0, 0.45), I 2 = 0%].…”

Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study

“…Of the seven age-treatment subgroup analyses that reported a statistically significant P value from an interaction test, two were from reviews with the same authors [39, 40]; otherwise, there was not a clear pattern of interventions, comparisons, and outcomes (Table 4). Six (6 of 7, 85.7%) were from reviews that outlined plans to conduct subgroup analyses in their methods sections.…”