2006
DOI: 10.1007/s00259-006-0066-x
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Abstract: This study shows that FDG uptake in the neck varies as a function of time, that it is unrelated to age or outdoor temperature, and that bilateral uptake is generally intense.

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Cited by 85 publications
(74 citation statements)
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“…Given this fact, it is not surprising that the literature on FDG uptake in human brown adipose tissue in relationship to outdoor temperature diverges; an earlier study (18) indicated a connection (more in winter), and a later study (62) did not find a connection. The latter is probably the more likely outcome; humans in present societies are rarely directly exposed to outdoor temperatures; much of our civilization even has this as its purpose (clothes and houses).…”
Section: Activity Is Induced By Acute Exposure To Coldmentioning
confidence: 89%
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“…Given this fact, it is not surprising that the literature on FDG uptake in human brown adipose tissue in relationship to outdoor temperature diverges; an earlier study (18) indicated a connection (more in winter), and a later study (62) did not find a connection. The latter is probably the more likely outcome; humans in present societies are rarely directly exposed to outdoor temperatures; much of our civilization even has this as its purpose (clothes and houses).…”
Section: Activity Is Induced By Acute Exposure To Coldmentioning
confidence: 89%
“…In a remarkable study, 33 women were systematically successively examined five times during an anticancer treatment. Apparently, only six of these women did not demonstrate brown adipose tissue labeling on any of these occasions, and only one woman demonstrated it on all five occasions (62). In this limited population, the prevalence of brown adipose tissue may then be said to be as high as 80%.…”
Section: The Prevalence Of Brown Adipose Tissue In Adult Manmentioning
confidence: 99%
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“…This point is highlighted by several studies showing poor reproducibility from subjects having multiple PET/CT scans. [35][36][37] Lee et al 35 reported that the average probability of obtaining subsequent positive PET/CT scans among patients with BAT was 13%. Similarly, in 33 subjects who each had 5 PET/CT scans, Rousseau et al 37 showed that FDG uptake was identical on all 5 scans in only 5 patients, ie, a 15% reproducibility.…”
Section: Limitations Of Pet/ct and Alternative Approaches For Assessimentioning
confidence: 99%
“…35,38 Currently, 18 F-FDG PET/CT scanning is the only "noninvasive" method for examining the presence of BAT. However, this technique is limited by poor reproducibility, [35][36][37]39 high cost, and the radiation exposure during the scan, which generally precludes the inclusion of healthy subjects in such studies. Therefore, there is a need to develop alternative noninvasive techniques for measuring the presence of BAT and, most important, BAT activity in humans.…”
Section: Limitations Of Pet/ct and Alternative Approaches For Assessimentioning
confidence: 99%