Bronchiectasis in a positive HIV child: a case report

Shrestha, L; Kanskar, P

doi:10.3126/joim.v35i1.8903

Journal of Institute of Medicine

2013

DOI: 10.3126/joim.v35i1.8903

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Bronchiectasis in a positive HIV child: a case report

L Shrestha¹,

P Kanskar²

Abstract: +XPDQ LPPXQRGH¿FLHQF\ YLUXV +,9 LQIHFWLRQ KDV D ZLGH VSHFWUXP RI SXOPRQDU\ GLVHDVH ZKLFK XVXDOO\ FRPSOLFDWHV WKH FOLQLFDO FRXUVH 1RQ F\VWLF ¿EURVLV EURQFKLHFWDVLV LV PRUH FRPPRQ LQ children with HIV infection than in general population. Bronchiectasis in children with HIV if not diagnosed early and managed aggressively can lead to irreversible destruction of bronchial ZDOO DQG VXUURXQGLQJ WLVVXH OHDGLQJ WR VLJQL¿FDQW PRUELGLW\ 7KLV PLJKW GHFUHDVH WKH EHQH¿W RI the antiretroviral therapy (ARV) treatment on the … Show more

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Cited by 2 publications

References 12 publications

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Predominance of CTX-M Type Extended Spectrum β-lactamase (ESBL) Producers Among Clinical Isolates of Enterobacteriaceae in a Tertiary Care Hospital, Kathmandu, Nepal

Lohani¹,

M²,

Sharma³

et al. 2019

TOMICROJ

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Background: ESBL problem is increasing worldwide and only limited studies on genes of ESBL are performed in Nepal. Objectives: We aimed to focus on the molecular detection of plasmid-mediated blaTEM, blaSHV and blaCTX-M genes among the ESBL producing Enterobacteriaceae from different clinical samples. Methods: A total of 550 clinical samples were processed and organisms of Enterobacteriaceae were identified using standard microbiological process. ESBL producers were screened and confirmed using modified Kirby Bauer disc diffusion method by CLSI guidelines. Plasmids extracted from the confirmed ESBL positives were the template for PCR. blaSHV, blaTEM and blaCTX-M genes were amplified using specific primers of respective genes by uniplex PCR. The presence of these genes was confirmed by gel electrophoresis. Results: Among 550 different clinical samples 343 (62.36%) were culture positive. Of which, 157 (45.57%) belonged to Enterobacteriaceae. Escherichia coli (45.9%) was predominant. Of these 33.2% (52/157) isolates ESBL positive. ESBL- E. coli (52.8%) were prevalent. All ESBL positive organisms were sensitive to imipenem. Of confirmed ESBL positives, 34.6% harboring blaTEM gene, 30.8% harboring blaSHV gene and blaCTX-M genes were present in all ESBL producers. Twenty-eightout of 52 (53.9%) isolates harbored multiple bla genes, the most common combination being blaCTX-M + blaTEM (21.2%). Conclusion: We report 100% plasmid mediated CTX-M genotype among ESBL producers which might indicate rapid dissemination of blaCTX-Mgenes from the community to the patients. Besides, there is a need for regular monitoring of antibiotic resistance in the country and de-escalate the use of antibiotics so as to preserve the antibiotics for future generation.

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Predominance of CTX-M Type Extended Spectrum β-lactamase (ESBL) Producers Among Clinical Isolates of Enterobacteriaceae in a Tertiary Care Hospital, Kathmandu, Nepal

Lohani¹,

M²,

Sharma³

et al. 2019

TOMICROJ

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Perceived Sources of Stress Among First-Year Nursing Students in Jordan

Shudifat¹,

Al-Husban²

2015

J Psychosoc Nurs Ment Health Serv

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The aim of the current study was to determine the most prevalent sources of stress among first-year nursing students at a military college in Jordan. A descriptive cross-sectional study was performed using a convenience sample of 138 students (females between ages 18 and 22). The Student Stress Survey was used to identify stressors and assess their relative importance. The instrument consists of 40 items divided into four categories of potential sources of stress: (a) intrapersonal, (b) interpersonal, (c) academic, and (d) environmental. Data were analyzed using descriptive statistics. The top five sources of stress reported were: increased class workload (89%), change in living environment (83%), change in social activities (78%), change in eating habits (77.5 %), and change in sleeping habits (76%), with academic sources of stress being the most frequently reported. The results provide valuable information for educators and administrators in nursing colleges to identify types of stress among first-year nursing students and establish strategies to reduce stress among such students, particularly from academic and environmental sources.

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Bronchiectasis in a positive HIV child: a case report

Cited by 2 publications

References 12 publications

Predominance of CTX-M Type Extended Spectrum β-lactamase (ESBL) Producers Among Clinical Isolates of Enterobacteriaceae in a Tertiary Care Hospital, Kathmandu, Nepal

Predominance of CTX-M Type Extended Spectrum β-lactamase (ESBL) Producers Among Clinical Isolates of Enterobacteriaceae in a Tertiary Care Hospital, Kathmandu, Nepal

Perceived Sources of Stress Among First-Year Nursing Students in Jordan

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