Breakthrough in the Treatment of Warts?

Breast Milk: A Source of Functional Compounds with Potential Application in Nutrition and Therapy

“…Microbial cultures [132] and transgenic animals [133] are used for large-scale production of the human variant of α-lactoalbumin. HAMLET has been used successfully in oncology: instilled in situ before resection of tumors in the bladder, improving the prognosis of this type of cancer [134]; in topical application in papillomas, achieving complete remission of lesions in more than 90% of treated patients and without significant side effects [135].…”

“…Complete remission of treated injuries in more than 90% of patients treated, without significant secondary effects. [135] Bovine lactoferrin Infant formula…”

Clinical applications of bioactive milk components

“…137 This result was sustained for 2 years after treatment cessation in 83% of HAMLET-treated patients, a result that has been hailed as a breakthrough in the treatment of human skin papillomas. 138 Methods for the large-scale production of HAMLET may include the expression of recombinant proteins in microorganisms 139 or transgenic cattle with scale-appropriate isolation systems. 140 Thus, HAMLET represents a novel antitumor therapy -derived from the study of milk -with remarkable clinical potential.…”

Protein–fatty acid complexes: biochemistry, biophysics and function

“…No adverse effects were reported . However, the study design and results received rather harsh criticism . HAMLET treatment was not compared to placebo‐ or conventional treatment because all patients received HAMLET treatment during the second phase of the trial.…”