volume 70, issue a1, PC1511-C1511 2014
DOI: 10.1107/s2053273314084885
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Koji Nagata, Nobuko Hongo, Yasuhiro Kameda, Akihiro Yamamura, Hiroshi Sasaki, Woo Cheol Lee, Kohki Ishikawa, Ei-ichiro Suzuki, Masaru Tanokura

Abstract: Brazzein, a 6.5-kDa protein consisting of 54 amino acids and four disulfide bonds, is the smallest sweet-tasting protein yet isolated from the wild African plant Pentadiplandra brazzeana. Brazzein has various desirable properties for use as a low-calorie sweetener in the diets of individuals suffering from diabetes, obesity, and metabolic syndrome. For example, brazzein has a high water solubility and a high thermostability. In addition, brazzein is 2000-times sweeter than sucrose on a weight basis. Both the s…

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