2009
DOI: 10.1001/archneurol.2009.29
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Cited by 8 publications

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“…When APP is moved into the endosome, it is cleaved by β -secretase and then transported either to the cell surface or to the lysosome to be further processed by γ -secretase to form beta amyloid. However, when APP accumulates at the cell surface, it has a greater chance of interacting with α -secretase to form nonamyloid-forming sAPP α [ 136 , 137 ].…”
Section: Discussion
mentioning
confidence: 99%