volume 93, issue 0, P2-S24-3 2020
DOI: 10.1254/jpssuppl.93.0_2-s24-3
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Abstract: Although some medicines to suppress the pain symptoms in fibromyalgia have been recently developed and used in clinic, the treatments remain to be fully satisfied. One of reasons may be attributed to the long-term use, which may cause side effects. Based on this point of view, we are studying the systems pathology on chronic pain. We have proposed the hypothesis that feed-forward amplification of pain mechanisms plays key roles in neuropathic pain. One of evidence is that self-amplification of lysophosphatidic…

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