Bowen disease associated with porokeratosis of Mibelli

Coskey, R. J.

doi:10.1001/archderm.111.11.1480

Cited by 16 publications

(12 citation statements)

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“…Neoplasms, particularly squamous cell carcinoma, basal cell carcinoma, and Bowen's disease, can develop. It is known to have about a 7.5% risk of developing cutaneous malignancies; patients with the linear type are at the greatest risk (19, 20–23).…”

Section: Discussionmentioning

confidence: 99%

Disseminated Superficial Actinic Porokeratosis with Both Typical and Prurigo Nodularis‐like Lesions

Kang

Kye

Kim

2001

The Journal of Dermatology

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We report a 50-year-old Korean patient who developed a disseminated superficial actinic porokeratosis (DSAP) with two types of lesions. One was a typical DSAP lesion clinically and histopathologically. The other was clinically similar to prurigo nodularis, but histologic examination showed the findings of porokeratosis such as cornoid lamellae and loss of the granular layer in addition to those of chronic lichenified dermatitis, so it could be described as prurigo nodularis-like porokeratosis. The nodular lesions seemed to develop on preexisting typical lesions of DSAP mainly during the summer by the aggravation of pruritic symptoms and scratching associated with sun exposure. Although we could not find any published reports describing lesions like those of our case, we think that such prurigo nodularis-like porokeratosis can develop in patients with DSAP in some situations involving pruritus and scratching.

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Section: Discussionmentioning

confidence: 99%

Disseminated Superficial Actinic Porokeratosis with Both Typical and Prurigo Nodularis‐like Lesions

Kang

Kye

Kim

2001

The Journal of Dermatology

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“…Usually, the lesions are characterized by single or multiple plaques, although typical elevated borders and variable atrophic central areas are observed. Malignant degeneration such as squamous cell carcinoma, basal cell carcinoma and Bowen's disease have been reported to be originated from lesions of porokeratosis 4–6 …”

Section: Discussionmentioning

confidence: 99%

Facial porokeratosis characterized by destructive lesions

Miranda

Filho

2004

Int J Dermatology

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Porokeratosis is a rare group of keratinizing diseases. It is inherited as an autosomal dominant disease with variable penetrance, although sporadic cases are often reported. Porokeratosis has as its histological hallmark the typical cornoid lamella. Porokeratosis lesions localized on the face can vary from superficial to destructive in nature. Only 12 cases have been reported in the literature to date. We report one more unusual case of destructive facial porokeratosis.

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“…Malignant neoplasms, including squamous cell carcinoma, 6,7 Bowen's disease 8 and BCC, 9 have been noted to arise in lesions of porokeratosis of Mibelli. Reports of the frequency of malignant transformation in lesions of porokeratosis vary from 7.5% 9 to 11.6% 10 .…”

Section: Discussionmentioning

confidence: 99%

Porokeratosis of Mibelli: Successful treatment with topical 5% imiquimod cream

Harrison

Sinclair

2003

Aust J Dermatology

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A 77-year-old woman with a large porokeratosis of Mibelli on the left shin was successfully treated with topical 5% imiquimod cream applied to the entire lesion once daily without occlusion three times a week. A strong inflammatory reaction was achieved in 6 weeks of treatment. The lesion had been present for approximately 6 years and prior treatments included curettage and electrocautery, cryotherapy and topical 5-fluorouracil under occlusion. At the end of treatment with topical 5% imiquimod cream, punch biopsy was negative for porokeratosis. The lesion healed without scarring. At 24-month follow up there had been no sign of clinical recurrence.

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Bowen disease associated with porokeratosis of Mibelli

Cited by 16 publications

References 0 publications

Disseminated Superficial Actinic Porokeratosis with Both Typical and Prurigo Nodularis‐like Lesions

Disseminated Superficial Actinic Porokeratosis with Both Typical and Prurigo Nodularis‐like Lesions

Facial porokeratosis characterized by destructive lesions

Porokeratosis of Mibelli: Successful treatment with topical 5% imiquimod cream

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