We provide an unconditional L 2 upper bound for the boundary layer separation of Leray-Hopf solutions in a smooth bounded domain. By layer separation, we mean the discrepancy between a (turbulent) low-viscosity Leray-Hopf solution u ν and a fixed (laminar) regular Euler solution ū with similar initial conditions and body force. We show an asymptotic upper bound C ū 3 L ∞ T on the layer separation, anomalous dissipation, and the work done by friction, which implies the drag coefficient of any object is bounded. This extends the previous result when the Euler solution is a regular shear in a finite channel. The key estimate is to control the boundary vorticity in a way that does not degenerate in the vanishing viscosity limit.