Botulinum toxin type A therapy for blepharospasm

Abstract

Editorial group: Cochrane Movement Disorders Group. Publication status and date: New search for studies and content updated (conclusions changed), published in Issue 11, 2020.

Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

“…There is potential for off-target muscle weakness or paralysis to lead to falls. However, our findings agree with the broader literature that demonstrates BoNT-A is well tolerated [ 24 , 25 , 52 , 53 ] and, when correctly administered, is considered very safe [ 54 ].…”

Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

“…There is potential for off-target muscle weakness or paralysis to lead to falls. However, our findings agree with the broader literature that demonstrates BoNT-A is well tolerated [ 24 , 25 , 52 , 53 ] and, when correctly administered, is considered very safe [ 54 ].…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Botulinum Neurotoxin Type a Injection Combined with Absorbable Punctal Plug Insertion: An Effective Therapy for Blepharospasm Patients with Dry Eye

“…Previous studies have confirmed the effect of BoNT-A injections in improving dry eye symptoms [1,15]. The medial lower pretarsal orbicularis oculi injections alleviate dry eye symptoms, although they are not indicated if the patient complains of watery eyes before treatment [39,41].…”

Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

“…There is potential for off-target muscle weakness or paralysis to lead to falls. However, our findings agree with the broader literature that demonstrates BoNT-A is well tolerated [ 24 , 25 , 52 , 53 ] and, when correctly administered, is considered very safe [ 54 ].…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Botulinum Neurotoxin Type a Injection Combined with Absorbable Punctal Plug Insertion: An Effective Therapy for Blepharospasm Patients with Dry Eye

“…Previous studies have confirmed the effect of BoNT-A injections in improving dry eye symptoms [1,15]. The medial lower pretarsal orbicularis oculi injections alleviate dry eye symptoms, although they are not indicated if the patient complains of watery eyes before treatment [39,41].…”

Pooled Safety Analysis of IncobotulinumtoxinA in the Treatment of Neurological Disorders in Adults

“…There is potential for off-target muscle weakness or paralysis to lead to falls. However, our findings agree with the broader literature that demonstrates BoNT-A is well tolerated [ 24 , 25 , 52 , 53 ] and, when correctly administered, is considered very safe [ 54 ].…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Botulinum Neurotoxin Type a Injection Combined with Absorbable Punctal Plug Insertion: An Effective Therapy for Blepharospasm Patients with Dry Eye

“…Previous studies have confirmed the effect of BoNT-A injections in improving dry eye symptoms [1,15]. The medial lower pretarsal orbicularis oculi injections alleviate dry eye symptoms, although they are not indicated if the patient complains of watery eyes before treatment [39,41].…”