Botulinum toxin type A therapy for blepharospasm

Abstract

Editorial group: Cochrane Movement Disorders Group. Publication status and date: New search for studies and content updated (conclusions changed), published in Issue 11, 2020.

Clinical features and treatment with botulinum toxin in blepharospasm: a 17-year experience

“…That difference was not found in HFS 19. Side effects occurred in 14% of patients in our sample, and most of them were mild and transient, agreeing with a systematic review that pointed to the safety of this therapeutic approach 17 . Finally, we did not observe any differences in symptom relief, duration or occurrence of side effects when we compared patients with isolated BPS and BPS plus other movement disorder, showing that they not only share the same clinical and demographic features but also therapeutic outcomes.…”

Clinical features and treatment with botulinum toxin in blepharospasm: a 17-year experience

“…That difference was not found in HFS 19. Side effects occurred in 14% of patients in our sample, and most of them were mild and transient, agreeing with a systematic review that pointed to the safety of this therapeutic approach 17 . Finally, we did not observe any differences in symptom relief, duration or occurrence of side effects when we compared patients with isolated BPS and BPS plus other movement disorder, showing that they not only share the same clinical and demographic features but also therapeutic outcomes.…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Effect of previous botulinum neurotoxin treatment on microvascular decompression for hemifacial spasm

“…2,8 As previously reported in the literature by Barbosa et al, 2 from 1993 to 2004 a total of 808 injections with botulinum neurotoxin were administered to 54 patients with HFS. The mean duration of improvement per application was 3.46 months and the mean rate of improvement using subjective judgment by the patient was 83%.…”

Clinical features and treatment with botulinum toxin in blepharospasm: a 17-year experience

“…That difference was not found in HFS 19. Side effects occurred in 14% of patients in our sample, and most of them were mild and transient, agreeing with a systematic review that pointed to the safety of this therapeutic approach 17 . Finally, we did not observe any differences in symptom relief, duration or occurrence of side effects when we compared patients with isolated BPS and BPS plus other movement disorder, showing that they not only share the same clinical and demographic features but also therapeutic outcomes.…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Effect of previous botulinum neurotoxin treatment on microvascular decompression for hemifacial spasm

“…2,8 As previously reported in the literature by Barbosa et al, 2 from 1993 to 2004 a total of 808 injections with botulinum neurotoxin were administered to 54 patients with HFS. The mean duration of improvement per application was 3.46 months and the mean rate of improvement using subjective judgment by the patient was 83%.…”

Clinical features and treatment with botulinum toxin in blepharospasm: a 17-year experience

“…That difference was not found in HFS 19. Side effects occurred in 14% of patients in our sample, and most of them were mild and transient, agreeing with a systematic review that pointed to the safety of this therapeutic approach 17 . Finally, we did not observe any differences in symptom relief, duration or occurrence of side effects when we compared patients with isolated BPS and BPS plus other movement disorder, showing that they not only share the same clinical and demographic features but also therapeutic outcomes.…”

Bolu Abant İzzet Baysal Üniversitesi Nöroloji Kliniğinde Botulinum Toksin Uygulamaları Deneyimleri

“…Studies conducted on patients with BS have shown that 90% improvement is achieved (30)(31)(32). In our clinic, as a result of the BoNT-A application, which was applied to 15 patients with BS, it was observed that a good level of improvement was achieved in all of the patients (Table 1).…”

Effect of previous botulinum neurotoxin treatment on microvascular decompression for hemifacial spasm

“…2,8 As previously reported in the literature by Barbosa et al, 2 from 1993 to 2004 a total of 808 injections with botulinum neurotoxin were administered to 54 patients with HFS. The mean duration of improvement per application was 3.46 months and the mean rate of improvement using subjective judgment by the patient was 83%.…”