Botanical Pharmacognosy of Centella asiatica (Linn.)Urban

Sudhakaran, Madathilparambil Vasu

doi:10.5530/pj.2017.4.88

Cited by 11 publications

(7 citation statements)

References 18 publications

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“…However, the presence of tracheid and trichome were reported for the first time. Reports are on (74) the presence of trichome and stomata in C. asiatica fresh leaves similar to our study in powdered form.…”

Section: Powder Microscopysupporting

confidence: 87%

Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

et al. 2022

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The use of plant-based drugs has increased considerably in the modern world for their efficiency in managing diseases with lesser side effects than synthetic drugs. The current study was aimed to confirm the identity, quality and purity of some locally available potential medicinal plants such as Alstonia scholaris (bark), Centella asiatica (whole plant), Drymaria cordata (whole plant), Hydrocotyle sibthorpioides (whole plant), Oroxylum indicum (bark), Senna hirsuta (leaf), Senna occidentalis (leaf), Solanum indicum (root), Stephania japonica (tuber) in powdered form. The powdered plant parts were evaluated for preliminary phytochemicals, pharmacognostical studies, physical characteristics and heavy metals. Preliminary phytochemical screening of the different extracts inferred the existence of carbohydrates, phenolics, alkaloids and amino acids while triterpenoids were absent. Microscopical study of the powder revealed the diagnostic qualities such as stone cells, trichomes, stomata, calcium oxalate crystal, fibres, xylem vessel, pitted spiral vessels, etc. The colour, odour, flavour/taste and texture of the pulverized plant were overall acceptable. The physical characteristics which determine the flow rate of the powder with respect to Carr’s index and Hausner’s ratio were found to be good to passable except for Hydrocotyle sibthorpioides (whole plant), Oroxylum indicum (bark), which were not easily passable. The heavy metal test showed the absence of bismuth, cadmium and lead. Thus the present study may serve as a standard reference for the quality control analysis of the herbal drug either singly or in synergy.

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Section: Powder Microscopysupporting

confidence: 87%

Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

et al. 2022

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“…Finalmente, como um dos principais fatores associados à doença de Parkinson é a agregação de α-sinucleína, sabe-se que o extrato aquoso de C. asiatica demonstrou impedir a formação desse oligômero e a consequente desintegração de fibrilas pré-formadas (Sudhakaran et al, 2017). É relatado, dessa forma, que esse adaptógeno possui a capacidade de prevenir a neurotoxicidade dopaminérgica vista na DP.…”

Section: Doença De Parkinsonunclassified

Como os adaptógenos influenciam a performance cognitivo-mental: uma revisão integrativa

Zago

Negro-Dellacqua²

2022

RSD

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Dada a alta demanda pela otimização do desempenho pessoal em vários aspectos da vida social e, tendo em vista as prevalentes situações de estresse da vida moderna, foram aperfeiçoados os adaptógenos, termo cunhado em 1943 pelos russos. O objetivo deste estudo é analisar essas substâncias “tônicas” que aumentavam a performance física em soldados durante a II Guerra Mundial, e que adquiriram uma nova abordagem nos anos seguintes, tomando espaço significativo na melhora da performance cognitivo-mental. Para tal, o estudo, uma revisão integrativa da literatura, será baseado nas plataformas científicas Scientific Eletronic Library Online – SCIELO, Google Acadêmico, a U. S. National Library of Medicine (NLM) - PubMed e ScienceDirect. Espera-se encontrar correlação entre o uso de adaptógenos na melhora da resposta a eventos estressores, promovendo, por fim, a performance cognitivo-mental. Os estudos demonstram que os adaptógenos apresentam ações positivas na memória, na função cognitiva e neuroproteção; também demonstram efeito ansiolítico, nootrópico e antiestresse. Dentre as doenças, há evidências de que os adaptógenos possam ter benefício na Doença de Parkinson e na de Alzheimer. A Ashwagandha, especialmente, recebe destaque nos estudos. Uma limitação do presente trabalho, é que a maioria dos estudos recentes obtidos como resultados foram também apresentados na forma de revisão da literatura, deixando claro que há necessidades de novas evidências científicas. Mesmo assim, os resultados corroboram para novas pesquisas relacionadas com a compreensão das propriedades terapêuticas dos adaptógenos, com foco, principalmente, em estudos clínicos.

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“…This development was first observed in developed countries three decades ago and has had a significant impact recently in developing countries as a major source and knowledge of nanotechnology and medicinal plants [1]- [3]. Lately, Japan has been the main importer of medicinal and aromatic plants from China and India which these two countries dominate the international supply of these plants [4]. One of the well-known marketed and extensively consumed medicinal plants is Centella Asiatica or frequently recognized as Indian pennywort or Pegagan [2], [5] or Pegagan in Indonesia [6].…”

Section: Introductionmentioning

confidence: 99%

Analyses of Bioactive Compounds of Pegagan (Centella Asiatica (L.) Urb) from Samosir – Indonesia Accession

Vinolina

Sigalingging

2022

Indonesian J. Agric. Res

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Centella Asiatica or Pegagan is classified as one of the wild plants that has not been domesticated. The excessive usage of this plant in traditional and modern medicinal applications threatens its population and sustainability. Thus, to preserve the plant and supply the high request of this plant in agromedicinal industry, studies concerned with the growth and bioactive compounds of Pegagan cultivated under commercial field conditions are urgently needed. This study purposed to examine the bioactive components of Pegagan (especially in leaves and roots) under field conditions, including asiaticoside, madeccasoside, and Asiatic acid. The Pegagan was harvested weeks after planting (WAP). The wet and dry weights of the leaves and roots were weighted and subsequently measured for their centelloside compounds by Thin-Layer Chromatography (TLC) procedure. The results revealed that the resulting asiaticoside content in the roots (1.25%) was higher than in the leaves (0.88%). The same results were achieved for the madecassoside content where the madecasosside content in the roots was 2.23%, while the content in the leaves was 2.11%. However, contrarily, the Asiatic acid compound in the leaves was 1.10% higher than the content in the roots (0.60%). It might be attributed to a longer period of field cultivation of Pegagan that delivered adequate time for the plant to alter Asiatic acid to asiaticoside and madecasosside at a later developmental growth. Moreover, these discoveries are advantageous in defining the most proper harvest time for commercial field cultivation of Pegagan to yield the highest amount of certain centelloside compounds.

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Botanical Pharmacognosy of Centella asiatica (Linn.)Urban

Cited by 11 publications

References 18 publications

Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

Characterisation of indigenous plants for herbal formulations preparation based on pharmacognostic and physiochemical data

Como os adaptógenos influenciam a performance cognitivo-mental: uma revisão integrativa

Analyses of Bioactive Compounds of Pegagan (Centella Asiatica (L.) Urb) from Samosir – Indonesia Accession

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