Boston Type 1 Keratoprosthesis: The University of California Davis Experience

Bradley, Jay; Hernandez, Enrique Graue; Schwab, Ivan R.; Mannis, Mark J.

doi:10.1097/ico.0b013e31818b8bfa

Cited by 175 publications

(165 citation statements)

References 12 publications

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“…Our series is also the largest study investigating predisposing peri-and postoperative factors predisposing to RD after implantation. Compared with other series, 1,5,7,19,20 ours shows a much higher incidence of RD, most likely because of the relatively large number of patients with longer follow-up and the higher incidence of autoimmune cases.…”

Section: Discussionmentioning

confidence: 80%

“…3,5,7,10 In our series, 84% of patients that developed an RD after implantation had RPMs, which are managed either by Nd:YAG capsulotomy or, in cases of recalcitrant membranes, by removal via pars plana vitrectomy. 3,5,6,20 Nd:YAG capsulotomy has been linked with a higher incidence of RD in pseudophakic eyes. 11,12 Thus, 58% of RD patients had a history of Nd:YAG laser capsulotomy prior to developing an RD.…”

Section: Retroprosthetic Membrane And/or Nd:yag Capsulotomymentioning

confidence: 99%

“…Relative risk (RR) of sterile vitritis, retroprosthetic membrane, and indication for surgery in the development of retinal detachment after KPro eyes, of which 28 were pseudophakic at the end of implantation. 5 …”

Section: Lens Statusmentioning

confidence: 99%

“…[2][3][4] Recent studies report postoperative visual acuity of better than 20/40 in up to 25% of patients undergoing the procedure. 1,5 However, secondary comorbidities, such as advanced glaucoma and vitreoretinal pathology, often lead to severe visual loss and failure of visual acuity to improve after keratoprosthesis implantation. 1 Retinal detachments, along with cystoid macular edema, macular epiretinal membranes, and retroprosthetic vitreous membranes, are vitreoretinal complications that can impair visual acuity after implantation.…”

mentioning

confidence: 99%

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Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes

et al. 2015

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Purpose-To determine the rates, predisposing factors, and visual outcomes of retinal detachment (RD) after Boston Keratoprosthesis (KPro) implantation.Methods-In this noncomparative, interventional case series, the medical records of 170 patients (205 eyes) who underwent Boston type 1 and type 2 KPro implantation at the Massachusetts Eye and Ear Infirmary between April 1993 and June 2009 were retrospectively reviewed. Incidence and annual rates of RD were calculated, and the roles of possible predictive factors for RD after KPro were investigated. Main outcome measures were rates of and risk factors for RD, visual acuity after RD, and surgical outcomes after repair.

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Section: Discussionmentioning

confidence: 80%

Section: Retroprosthetic Membrane And/or Nd:yag Capsulotomymentioning

confidence: 99%

Section: Lens Statusmentioning

confidence: 99%

mentioning

confidence: 99%

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Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes

et al. 2015

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“…Although direct comparison of all these devices is inappropriate because of variations in disease indications and severity, several articles reporting results with these KPros have been published. 28,29,[31][32][33][34][35][36] In assessing these devices, visual outcomes and anatomic success in terms of KPro retention are especially important. Results with OOKP are promising, with good device retention, good visual performance, and relative paucity of devicerelated complications, 35,36 but it is relatively complicated 2(3)-stage procedure insisting return visits to operating room with delayed visual recovery.…”

Section: Discussionmentioning

confidence: 99%

AlphaCor artificial cornea: clinical outcome

Jirásková

Rozsíval

Burova

et al. 2011

Eye

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Purpose The purpose of this study was to describe the long-term results of AlphaCor implantations, and to evaluate the main complications and risk factors. Methods Retrospective analysis of preoperative and follow-up data from 15 AlphaCor implantations. Analysis of outcomes, trends, and associations was performed and compared with data from published clinical trials and a literature review.Results The survival rate of the device at 1, 2, and 3 years was 87%, 58%, and 42%, respectively. Postoperative visual acuity ranged from hand movement to 0.8. The most significant complications were stromal melt (nine cases), optic deposition (three eyes), and retroprosthetic membrane formation (three eyes). The most common device-unrelated complication was trauma (three patients). All complications were managed without loss of the eye. Conclusion AlphaCor provides a treatment option for patients with corneal blindness in which a donor tissue graft would not succeed.

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Vitreoretinal Surgery in the Setting of Permanent Keratoprosthesis

Sippel¹

2012

Arch Ophthalmol

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To evaluate the surgical management of vitreoretinal pathology in patients with a permanent Boston Type 1 keratoprosthesis (hereafter referred to as a KPro) in the era of small-gauge vitrectomy techniques.Methods: Retrospective review of 23 small-gauge vitreoretinal surgical procedures during or after Dohlman-Doane KPro placement in 14 eyes.Results: Established and innovative techniques were used, including sutureless small-gauge vitrectomy, temporal positioning of surgeon, long-term tamponades, and exploratory endoscopy. Retro-KPro membranes formed less frequently when vitrectomy was performed during KPro placement. Anatomical goals were achieved, and no serious complications directly resulted from these techniques. Visual acuity, frequently limited by preexisting pathology, improved in most cases.Conclusions: Modern posterior segment surgical techniques, including small-gauge sutureless vitrectomy, can be effectively used for patients with a permanent KPro. Vitrectomy and glaucoma tube revision by a team of subspecialists at the time of KPro placement may reduce subsequent complications.

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Boston Type 1 Keratoprosthesis: The University of California Davis Experience

Cited by 175 publications

References 12 publications

Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes

Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes

AlphaCor artificial cornea: clinical outcome

Vitreoretinal Surgery in the Setting of Permanent Keratoprosthesis

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