volume 68, issue 3, P786-799 2008
DOI: 10.1111/j.1365-2958.2008.06204.x
View full text
|
|
Share

Abstract: SummarySpirochetes living in an oxygen-rich environment or when challenged by host immune cells are exposed to reactive oxygen species (ROS). These species can harm/destroy cysteinyl residues, iron-sulphur clusters, DNA and polyunsaturated lipids, leading to inhibition of growth or cell death. Because Borrelia burgdorferi contains no intracellular iron, DNA is most likely not a major target for ROS via Fenton reaction. In support of this, growth of B. burgdorferi in the presence of 5 mM H2O2 had no effect on …

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

6
102
0
2

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals