Booster dose vaccination for preventing hepatitis B

Comparison between two population-based hepatitis B serosurveys with an 8-year interval in Shandong Province, China

“…In this study, 65.59% of students in the 2014 survey were born after universal infant hepatitis B vaccination and 76.34% had received the hepatitis B vaccination. The necessity of hepatitis B vaccine booster doses among healthy individuals remains controversial (Poorolajal and Hooshmand, 2016). However, according to the present results, it may be necessary to provide hepatitis B vaccination to students over 18 years of age who have not completed three doses of hepatitis B vaccine and to conduct studies on the booster dose among those who have completed a full course of hepatitis B vaccine in infancy.…”

Comparison between two population-based hepatitis B serosurveys with an 8-year interval in Shandong Province, China

“…In this study, 65.59% of students in the 2014 survey were born after universal infant hepatitis B vaccination and 76.34% had received the hepatitis B vaccination. The necessity of hepatitis B vaccine booster doses among healthy individuals remains controversial (Poorolajal and Hooshmand, 2016). However, according to the present results, it may be necessary to provide hepatitis B vaccination to students over 18 years of age who have not completed three doses of hepatitis B vaccine and to conduct studies on the booster dose among those who have completed a full course of hepatitis B vaccine in infancy.…”

Hepatitis B vaccination policies for health‐care workers: Need for a worldwide consensus

“…Furthermore, the Cochrane database systematic review from 2016 concluded that there is no scientific evidence to support or reject the need for booster doses of HB vaccine in healthy individuals with normal immune status. 10 The immunological memory decades after immunization needs further investigation. Definitely, more research is needed on the vaccination strategies (including serotesting) for (student) HCWs already vaccinated as an infant, child, or adolescent.…”

Seroprevalence of anti-HBs antibodies at young adulthood, before and after a booster vaccine dose, among medical personnel vaccinated in infancy

“…Thus, revaccination policies remain controversial and suboptimally informed by evidence, and practices vary from country to country [11,32]. In light of the lack of randomized clinical trials evaluating the anamnestic response to booster doses, a recent Cochrane Review concluded that there is no scientific evidence to support or reject the need for booster doses of HBV vaccine in healthy individuals with normal immune status [33]. Thus, the UK recommends a single booster dose 5 years after primary vaccination [34], while the US-CDC recommends that no routine booster is necessary [35].…”

Comparison between two population-based hepatitis B serosurveys with an 8-year interval in Shandong Province, China

“…In this study, 65.59% of students in the 2014 survey were born after universal infant hepatitis B vaccination and 76.34% had received the hepatitis B vaccination. The necessity of hepatitis B vaccine booster doses among healthy individuals remains controversial (Poorolajal and Hooshmand, 2016). However, according to the present results, it may be necessary to provide hepatitis B vaccination to students over 18 years of age who have not completed three doses of hepatitis B vaccine and to conduct studies on the booster dose among those who have completed a full course of hepatitis B vaccine in infancy.…”

Hepatitis B vaccination policies for health‐care workers: Need for a worldwide consensus

“…Furthermore, the Cochrane database systematic review from 2016 concluded that there is no scientific evidence to support or reject the need for booster doses of HB vaccine in healthy individuals with normal immune status. 10 The immunological memory decades after immunization needs further investigation. Definitely, more research is needed on the vaccination strategies (including serotesting) for (student) HCWs already vaccinated as an infant, child, or adolescent.…”

Seroprevalence of anti-HBs antibodies at young adulthood, before and after a booster vaccine dose, among medical personnel vaccinated in infancy

“…Thus, revaccination policies remain controversial and suboptimally informed by evidence, and practices vary from country to country [11,32]. In light of the lack of randomized clinical trials evaluating the anamnestic response to booster doses, a recent Cochrane Review concluded that there is no scientific evidence to support or reject the need for booster doses of HBV vaccine in healthy individuals with normal immune status [33]. Thus, the UK recommends a single booster dose 5 years after primary vaccination [34], while the US-CDC recommends that no routine booster is necessary [35].…”

Comparison between two population-based hepatitis B serosurveys with an 8-year interval in Shandong Province, China

“…In this study, 65.59% of students in the 2014 survey were born after universal infant hepatitis B vaccination and 76.34% had received the hepatitis B vaccination. The necessity of hepatitis B vaccine booster doses among healthy individuals remains controversial (Poorolajal and Hooshmand, 2016). However, according to the present results, it may be necessary to provide hepatitis B vaccination to students over 18 years of age who have not completed three doses of hepatitis B vaccine and to conduct studies on the booster dose among those who have completed a full course of hepatitis B vaccine in infancy.…”

Hepatitis B vaccination policies for health‐care workers: Need for a worldwide consensus

“…Furthermore, the Cochrane database systematic review from 2016 concluded that there is no scientific evidence to support or reject the need for booster doses of HB vaccine in healthy individuals with normal immune status. 10 The immunological memory decades after immunization needs further investigation. Definitely, more research is needed on the vaccination strategies (including serotesting) for (student) HCWs already vaccinated as an infant, child, or adolescent.…”

Seroprevalence of anti-HBs antibodies at young adulthood, before and after a booster vaccine dose, among medical personnel vaccinated in infancy

“…Thus, revaccination policies remain controversial and suboptimally informed by evidence, and practices vary from country to country [11,32]. In light of the lack of randomized clinical trials evaluating the anamnestic response to booster doses, a recent Cochrane Review concluded that there is no scientific evidence to support or reject the need for booster doses of HBV vaccine in healthy individuals with normal immune status [33]. Thus, the UK recommends a single booster dose 5 years after primary vaccination [34], while the US-CDC recommends that no routine booster is necessary [35].…”