Bone Lesions in Kaposi's Sarcoma

Ronchese, F

doi:10.1001/archderm.1954.01540210082013

Cited by 9 publications

(2 citation statements)

References 4 publications

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“…KS-related osteolysis manifested as uniform rarefaction, cystic lesions, or complete bone destruction. 35,48 Cortical bone erosion was either caused by KS arising in the cortex or periosteum, or it occurred secondary to external pressure from an adjacent soft tissue and/ or cutaneous KS tumor. Cortical lesions and adjacent soft tissue masses also were identified more easily with MRI than with CT scans.…”

Section: Discussionmentioning

confidence: 99%

Kaposi sarcoma of the musculoskeletal system

Caponetti

Dezube

Restrepo

et al. 2007

Cancer

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Kaposi sarcoma (KS) of bone and skeletal muscle is unusual. In this report, the authors review 66 published patients with KS who had involvement of the musculoskeletal system reported from 1925 to 2006. In only 3 patients was acquired immunodeficiency syndrome (AIDS)-related KS identified within skeletal muscle.Osseous KS lesions were more frequent and occurred with African, classic, and AIDS-related KS and occurred rarely in transplantation-associated KS. Patients seldom were asymptomatic. They usually had bone pain with limited mobility or infrequently developed serious sequelae like spinal cord compression. Locally aggressive African and classic KS lesions typically involved the peripheral skeleton; whereas, in patients with AIDS, the axial (vertebrae, ribs, sternum, and pelvis) and/or maxillofacial bones more commonly were involved. Almost all patients had concomitant nonosseous KS lesions. Joint involvement was exceptional, and pathologic fractures were not observed. Computed tomography scans and magnetic resonance images were better at detecting osseous KS lesions, which frequently went undetected on plain x-ray films or bone scans. Pathologic diagnosis was important to exclude similar lesions like bacillary angiomatosis.Treatment options, including surgery and, in more recent patients, radiation and/or chemotherapy, had limited success.

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Section: Discussionmentioning

confidence: 99%

Kaposi sarcoma of the musculoskeletal system

Caponetti

Dezube

Restrepo

et al. 2007

Cancer

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“…Involvement of the lymph nodes [2,5,30], larynx, pharynx [26], bones [31,35] lungs [18], brain [34], gastrointestinal tract (the latter resulting in extensive hemorrhage and partial obstruction), has been reported. The diag nosis of visceral lesions, which may remain clinically silent for a long time often proves difficult and in most cases is only made after histopathological examination of surgical or postmortem specimens [8,28,36].…”

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confidence: 99%