Bone defects of the jaws: moving from reconstruction to regeneration

Kyriakidou, E.; O’Connor, N.; Malden, N; Lopes, Victor

doi:10.12968/denu.2014.41.7.613

Cited by 4 publications

(2 citation statements)

References 26 publications

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“…This deficiency is due to several reasons, the most important of which are periodontal tissue diseases, cysts, and severe surgical trauma during extraction. 1 Several techniques have been described to compensate for and speed up the healing of defective bone for the purpose of placing dental implants or avoiding fracture or deformation of the bone. 2 Xenografts, such as inorganic bovine bone grafts, have been widely used to achieve three-dimensional healing of the maxillary bone in the field of repair of defects and alveolar resorption in several studies.…”

Section: Introductionmentioning

confidence: 99%

Case Report: The effect of bone morphogenetic proteins (BMP) in comparison with a xenograft in the management of mandibular bone defects

Alhalabi,

Zenati

2024

F1000Res

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Background This study aims to compare the effect of Bone Morphogenetic Proteins (rhBMP), carried on a gelatin sponge scaffold in comparison with the Xenograft BioOss® in the management of mandibular bone defects. Case presentation The case is a 48-year-old woman who had 2 cysts in the mandibular bone, BMP2 was placed within the first hole with a gelatin sponge, and a BioOss® graft was placed within the second defect. The radiographic evaluation was conducted before and after surgery and 1, 3, and 6 months after the surgical work. Histological assessment was conducted after 6 months of the surgical work. Results The results of the radiographic evaluation found that there was no big difference between the healing in the holes filled with rhBMP2 with gelatin sponge and the healing in the holes filled with BioOss®. Conclusion The use of a gelatin sponge impregnated with Bone Morphogenetic Proteins improves and accelerates the healing of bone defects and is comparable to the effectiveness of using a BioOss® graft.

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Section: Introductionmentioning

confidence: 99%

Case Report: The effect of bone morphogenetic proteins (BMP) in comparison with a xenograft in the management of mandibular bone defects

Alhalabi,

Zenati

2024

F1000Res

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“…To prevent the development of severe bone resorption and provide an adequate bone height and width for successive implant rehabilitation, numerous surgical techniques have been proposed, such as alveolar ridge preservation (ARP) or guided bone regeneration procedures (GBR) [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

Mauceri

Murgia

Cicero³

et al. 2021

Medicina

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The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.

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The effect of bone morphogenetic proteins BMP in comparison with A Xenograft in the management of bone defects

Lutfallah,

Mazen

2023

Glob J Medical Clin Case Rep

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Background: The aim of this study is to compare the effect of Bone Morphogenetic Proteins (rhBMP), carried on a gelatin sponge scaffold in comparison with the Xenograft BioOss® in the management of bone defects. Case presentation: The case is a one-year-old rabbit that had 4 identical holes 5*5 mm within the femur bone, BMP2 was placed within the first hole with a gelatin sponge, and the second defect was left empty. A gelatin sponge was placed alone within the third hole, and a BioOss® graft was placed within the last defect. The radiographic evaluation was conducted (1 and 2) months after the surgical work, and the histological assessment was conducted two months after the surgical work. Results: The results of the radiographic evaluation found that healing the BMP2 hole was better than healing in the empty and the gelatin sponge group holes. There was no big difference between the healing in the holes filled with rhBMP2 with gelatin sponge and the healing in the holes filled with BioOss®. Conclusion: The use of a gelatin sponge impregnated with Bone Morphogenetic Proteins improves and accelerates the healing of bone defects and is comparable to the effectiveness of using a BioOss® graft.

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Bone defects of the jaws: moving from reconstruction to regeneration

Cited by 4 publications

References 26 publications

Case Report: The effect of bone morphogenetic proteins (BMP) in comparison with a xenograft in the management of mandibular bone defects

Case Report: The effect of bone morphogenetic proteins (BMP) in comparison with a xenograft in the management of mandibular bone defects

Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

The effect of bone morphogenetic proteins BMP in comparison with A Xenograft in the management of bone defects

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