Bone cement usage modalities at a multi-site university hospital centre

Barral, Marine; Lalande, Laure; Viste, Anthony; Besse, Jean-Luc; Fessy, Michel‐Henri; Carré, E.

doi:10.1016/j.otsr.2018.11.022

Cited by 6 publications

(4 citation statements)

References 21 publications

(24 reference statements)

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“…Gentamicin‐containing bone cement is the most commonly used AIBC in Australian hospitals, a finding which has been reported previously 20 . Tobramycin is another aminoglycoside‐containing AIBC that was reported by 18% ( n = 15) of 82 survey respondents as being included in their hospitals' inventory.…”

Section: Discussionsupporting

confidence: 53%

“…Gentamicin-containing bone cement is the most commonly used AIBC in Australian hospitals, a finding which has been reported previously. 20 Tobramycin is another aminoglycoside-containing AIBC that was reported by 18% (n = 15) of 82 survey respondents as being included in their hospitals' inventory. Although limited information was retrieved in this study regarding additional antimicrobials that are added to cement by the surgeon in theatre, in the United States it is common for additional tobramycin to be added to cement as the injectable formulation is available in the United States in a powdered form.…”

Section: Discussionmentioning

confidence: 99%

“…21 From review studies, tobramycin is reportedly the preferred aminoglycoside in the United States should the surgeon require a higher dose of the aminoglycoside in the bone cement. 20 In Australia, both gentamicin and tobramycin are only available in injectable solutions.…”

Section: Discussionmentioning

confidence: 99%

“…Although limited information was retrieved in this study regarding additional antimicrobials that are added to cement by the surgeon in theatre, in the United States it is common for additional tobramycin to be added to cement as the injectable formulation is available in the United States in a powdered form 21 . From review studies, tobramycin is reportedly the preferred aminoglycoside in the United States should the surgeon require a higher dose of the aminoglycoside in the bone cement 20 . In Australia, both gentamicin and tobramycin are only available in injectable solutions.…”

Section: Discussionmentioning

confidence: 99%

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Antimicrobial‐impregnated bone cement use in Australian hospitals: scoping pharmacist awareness and involvement in management

Teoh

Hillock

2022

Pharmacy Practice and Res

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Background: Antibiotic-impregnated bone cement (AIBC) is frequently used in arthroplasty surgery to minimise the risk of infection in the prosthetic knee or hip joint. Aim: To gain greater insight into the use, documentation, and stock-management of AIBC in Australian hospitals. Method: A mixed-methods study was conducted. Antimicrobial surveillance data were analysed to identify Australian hospitals including AIBC in their monthly pharmacy data submissions. An online survey was distributed to pharmacists registered with the National Antimicrobial Utilisation Surveillance Program to investigate knowledge of the use, documentation, and stock-management of bone cement. Results: Surveillance data from January to June 2021 showed 13% (n = 28) of the 222 participating hospitals included bone cement in their antimicrobial usage data. All reported AIBC usage data contained an aminoglycoside antibiotic. Fifty-two pharmacists responded (17% response rate) to the online survey. When asked about inventory, 35% of participants stated that their hospital pharmacies manage bone cements. Of 82 responses, 6% (n = 5) had knowledge of additional antibiotics or antifungals loaded into bone cements intraoperatively. More than half of the respondents reported that documentation of AIBC use was unclear, while others knew to search for it in prosthesis or theatre notes. Conclusion:This study has illustrated a gap in pharmacists' knowledge in the perioperative setting regarding the use and documentation of bone cement, and highlights a possible focus for future education to assist with antimicrobial stewardship in this setting. Consistency in the management and documentation of AIBC would assist in surveillance of usage, help identify variations in practice and provide opportunities for quality improvement.

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%