2015
DOI: 10.1055/s-0035-1554964 View full text |Buy / Rent full text
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Abstract: In this study, low BMI was an independent risk factor for mortality, and the incidence of cerebrovascular and pulmonary complications tended to be higher in patients with low BMI than in obese patients. Underweight patients should be closely monitored following pulmonary resection.

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“…Interestingly, low BMI was associated with poor outcome, particularly in underweight patients. Although previous studies showed similar results3536, the precise mechanism underlying this observation has not yet been clarified. These findings are, however, comparable to those of other chronic lung diseases, such as chronic obstructive lung disease and idiopathic pulmonary fibrosis3738, and a possible explanation may be related to the effect of several cytokines or malnutrition3940.…”
Section: Discussionmentioning
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“…Interestingly, low BMI was associated with poor outcome, particularly in underweight patients. Although previous studies showed similar results3536, the precise mechanism underlying this observation has not yet been clarified. These findings are, however, comparable to those of other chronic lung diseases, such as chronic obstructive lung disease and idiopathic pulmonary fibrosis3738, and a possible explanation may be related to the effect of several cytokines or malnutrition3940.…”
Section: Discussionmentioning
“…First, underweight patients had a more advanced cancer stage (stage III). Because advanced cancer requires higher basal metabolic demand and energy consumption [ 21 , 22 ], these patients conferred higher risk of preoperative rapid weight loss, affecting their health and immune system and leaving them in an adverse physiologic state [ 8 , 15 ]. Hence, underweight patients may experience weight loss caused by cancer, leading to adverse outcomes.…”
Section: Discussionmentioning
“…To this end, gastric cancer patients with higher BMI undergoing gastrectomy demonstrate significantly better survival rates compared to those with a BMI within the standard range [ 44 ]. Similarly, low BMI was demonstrated as an independent risk factor for increased mortality and co-incidence of cerebrovascular and pulmonary complications in resected lung cancer patients compared to their obese counterparts [ 82 ]. Underweight is suggested to be a predictor of poorer overall survival of colorectal cancer patients being potentially associated with poor performance status and decreased effectiveness of both the surgical and chemotherapeutic treatments [ 83 ].…”
Section: Cancersmentioning