BMI is Strongly Associated With Hypertension, and Waist Circumference is Strongly Associated With Type 2 Diabetes and Dyslipidemia, in Northern Chinese Adults

Abstract

BackgroundObesity is closely associated with chronic diseases such as hypertension, type 2 diabetes mellitus (T2DM), and dyslipidemia. We analyzed the optimal obesity index cut-off values for metabolic syndrome (MetS), and identified the obesity index that is more closely associated with these chronic diseases, in a population of northern Chinese.MethodsWe surveyed 8940 adults (age, 20–74 years) living in northern China for chronic diseases. Receiver operating characteristics (ROC) analysis, relative risk, and multivariate regression were used to develop an appropriate index and optimal cut-off values for MetS and obesity-related chronic diseases.ResultsWaist circumference (WC) and body mass index (BMI) were good markers for MetS, WC was a good marker for T2DM and dyslipidemia, and BMI was a good marker for hypertension. The optimal BMI cut-off value of MetS was 24 kg/m2, and the optimal WC cut-offs were 86 cm and 78 cm in men and women, respectively. Relative risk regression models showed that BMI was associated with hypertension, T2DM, and hypertriglyceridemia and a higher prevalence ratio (PR) for hypertension: 2.35 (95% CI, 2.18–2.50). WC was associated with T2DM, hypertension, and hypertriglyceridemia, with PRs of 2.05 (1.63–2.55) for T2DM and 2.47 (2.04–2.85) for hypertriglyceridemia. In multivariate regression models, the standardized regression coefficients (SRCs) of BMI were greater for SBP and DBP, and the SRC of WC was greater for fasting blood glucose, 2-hour postload blood glucose, triglyceride, and total cholesterol.ConclusionsOur analysis of a population of northern Chinese indicates that the optimal cut-off values for MetS are WCs of 86 cm in men and 78 cm in women and a BMI of 24 kg/m2 in both sexes. BMI was strongly associated with hypertension, while WC was strongly associated with T2DM and dyslipidemia.

Diabetes Mellitus tipo 2: caracterização da assistência à saúde, parâmetros clínicos e estado nutricional de idosos em uma Unidade Básica de Saúde, em dois períodos de acompanhamento

“…Segundo o Consenso Brasileiro de Diabetes (2014)(2015), publicado pela Sociedade Brasileira de Diabetes, estima-se a existência de 382 milhões de indivíduos com DM no mundo, com previsão de progressão para 471 milhões em 2035. Tais números são indicativos de uma "epidemia" da doença, com dados crescentes na população mais jovem em países em desenvolvimento (SOCIEDADE BRASILEIRA DE DIABETES, 2015).…”

“…Aparentemente, durante o diagnóstico, a idade pode influenciar no agravamento da doença e no aparecimento de complicações associadas (KALYANI & EGAN, 2013 2015).…”

“…Segundo a Sociedade Brasileira de Diabetes (2015), o diagnóstico de DM pode ser realizado através da dosagem de glicemia de jejum com valor maior ou igual a 126 mg/dl; glicemia de duas horas com valor igual ou superior a 200 mg/dl, pós-sobrecarga de 75g de ! 23!…”

“…Em relação à classificação do excesso de peso, ressalta-se a dificuldade da utilização do Índice de Massa Corporal (IMC) como parâmetro único, pelo fato de não discriminar a composição corporal do indivíduo, desconsiderando os percentuais de massa magra e massa gorda (FENG et al, 2012).…”

“…circunferência da cintura e o DM tipo 2 e as dislipidemias, especialmente por tal medida avaliar o tecido adiposo em região intra-abdominal. O acúmulo deste tipo de gordura é associado às doenças cardiovasculares, DM tipo 2, dislipidemias e hipertensão arterial (FENG et al, 2012: AZARBAD & GONDER-FREDERICK, 2010).…”