Blocking or enhancing effects of some basic emollients in UVA penetration

Abstract

BackgroundTopical agents used in combination with phototherapy or photochemotherapy may have both blocking or enhancing effects in ultraviolet rays.ObjectiveIn this in vivo study, the effects of topical petrolatum, basis cream, glycerine, and olive oil on the transmission of ultraviolet A radiation were investigated.MethodsA test was performed to determine the minimal phototoxic dose on 29 volunteers with only psoralen plus ultraviolet A (PUVA) and then the same test was repeated with white petrolatum, basis c…