1971
DOI: 10.1001/archderm.104.5.508
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Bleomycin in mycosis fungoides and reticulum cell lymphoma

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1973
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Cited by 8 publications
(4 citation statements)
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“…Histology of the indurated lesions shows dense collagen with areas of homogenization espeeially around vessels and adnexal structures (35). These sclerotic changes, which appear to be unique to bleorrrycin, have been reported to be reversible when the drug is elinninated (37).…”
Section: Sclerodermoid Disordersmentioning
confidence: 99%
“…Histology of the indurated lesions shows dense collagen with areas of homogenization espeeially around vessels and adnexal structures (35). These sclerotic changes, which appear to be unique to bleorrrycin, have been reported to be reversible when the drug is elinninated (37).…”
Section: Sclerodermoid Disordersmentioning
confidence: 99%
“…This drug, which is used in the treatment of various reticuloses, may cause hyperpigmentation of the skin lesions (De Bast et al, 1971). Excoriations also may become pigmented (British Medical Journal, 1972).…”
Section: Bleomycinmentioning
confidence: 99%
“…Unique skin and pulmonary lesions are major limiting adverse reactions.'" 8,18,20 These lesions are probably related to the unique preferential concentration of bleomycin in the skin and lungs as well as tumors of epithelial origin. Some of the unique skin reactions are: increased pigmentation, urticaria, erythema, swelling, tenderness, and sclerodermoid changes in the skin.…”
mentioning
confidence: 99%