Bisphenol A regulates bladder cells responses via control of G2/M‐phase cell cycle, apoptotic signaling, MAPK pathway, and transcription factor‐associated MMP modulation
Jun‐Hui Song,
Byungdoo Hwang,
Solbi Park
et al.
Abstract:Bisphenol A (BPA), an exogenous endocrine‐disrupting chemical, is widely used to produce polycarbonate plastics. The widely used BPA has been detected in human urine samples, raising public anxiety about the detrimental effects of BPA on the bladder. In this study, we explored regulatory mechanisms for the adverse effects of BPA in human bladder BdFC and T24 cells. BPA induced extrinsic and intrinsic apoptosis and G2/M cell cycle arrest caused by the ATM‐CHK1/CHK2‐CDC25c‐CDC2 signaling, which ultimately inhibi… Show more
This study evaluated the immunostimulatory potential of garlic fermented with Bacillus subtilis (Aglio) and identified the underlying mechanisms using in vitro and in vivo models.
This study evaluated the immunostimulatory potential of garlic fermented with Bacillus subtilis (Aglio) and identified the underlying mechanisms using in vitro and in vivo models.
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