1923
DOI: 10.1001/archderm.1923.02360120026002
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Bismuth in the Treatment of Syphilis

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“…This could explain the low values of MPO observed in this study for the bismuth exposed neutrophils. Historically, bismuth subnitrate was used by intramuscular injection for treatment of syphilis [30]. If bismuth subnitrate had induced chemotaxis and activation of neutrophils when injected intramuscularly, the site of injection would have been swollen and inflamed.…”
Section: Discussion
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confidence: 99%